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Myasthenia Gravis Masquerading as a Third Cranial Nerve Palsy

1 February 2014 |
A 65-year-old man presented with a week’s history of binocular diplopia (in all directions of gaze) and a right partial ptosis. He was systemically well. His past medical history was unremarkable except for vitiligo. At presentation acuity was 6/6 bilaterally....

Intravitreal afibercept and ranibizumab for PCV

1 August 2016 | | EYE - Vitreo-Retinal
This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...

Orbital cellulitis in Scotland: current incidents, aetiology, management and outcomes

1 February 2015 | | EYE - Oculoplastic, EYE - Orbit
This is a one year prospective study using the Scottish ophthalmic surveillance unit reporting system amongst Scottish ophthalmologists. Only patients residing within Scotland with a new diagnosis of orbital cellulitis between November 2011 and October 2012 were including in this...

In conversation with Dr Robert B Nussenblatt

1 February 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...

Traumatic optic neuropathy

1 October 2021 | | EYE - Orbit, EYE - Neuro-ophthalmology, EYE - General
In neuro-ophthalmology we get asked a lot about management of patients who suffered significant trauma and presented with loss of vision secondary to presumed traumatic optic neuropathy (TON). TON happens usually in the context of significant craniofacial trauma. The incidence...

Neurofibromatosis type 2 – diagnosis, features and MDT approach

1 December 2021 | | EYE - Orbit, EYE - Vitreo-Retinal, EYE - Cataract, EYE - Refractive, EYE - General
NF2 is a genetic condition caused by mutation in a single gene (NF2 gene) on chromosome 22. The NF2 gene provides instructions to produce a protein called merlin, also known as schwannomin. This protein functions as a tumour suppressor, preventing...

Demyelinating optic neuropathy

5 June 2023 | | EYE - Neuro-ophthalmology, EYE - General
Introduction Optic neuritis (ON) is an inflammatory process affecting the optic nerve. After glaucoma, it is the most common optic neuropathy affecting patients under the age of 50. The usual presentation of typical ON is unilateral subacute loss of vision...

Lockdown and eye health – a case of accommodative spasm

6 April 2021 | | EYE - Orbit, EYE - Imaging, EYE - General
A 25-year-old male presented to the eye casualty with a one-day history of sudden onset worsening vision. More specifically, he noted his vision was more blurred than usual and this was more exaggerated for near-work than for distance-work. He was...

Vitreomacular traction: natural course vs. vitrectomy vs. ocriplasmin

3 June 2024 | | EYE - Vitreo-Retinal
Over time, the vitreous gel completely separates from the retina in a process known as a posterior vitreous detachment (PVD). In some instances, however, the vitreous does not detach entirely and remains adherent to the macula. The term vitreomacular traction...

Sclerochoroidal calcification masquerading as ocular malignancy

5 April 2022 | | EYE - Vitreo-Retinal, EYE - General
Case 1 A 68-year-old Caucasian gentleman was urgently referred to eye casualty by his optometrist after seeing an unusual incidental finding of protruding lesions from the retina, suspecting choroidal melanoma. He was asymptomatic and this was his first eye test...

Optic nerve swelling – your survival guide (part 2)

1 December 2017 | | EYE - Neuro-ophthalmology
In this second article we will discuss bilateral optic nerve swelling, its aetiology, various investigations and possible treatments. We will also discuss various protocols used in the management of suspected optic nerve swelling cases. (Part one of this topic available...

The Leicester Grading System for Foveal Hypoplasia

1 April 2020 | | EYE - Paediatrics, EYE - Neuro-ophthalmology, EYE - Orbit, EYE - General
The University of Leicester Ulverscroft Eye Unit have published the first medical grading system named after the city of Leicester. Infantile nystagmus is characterised by constant and involuntary eye movements and affects 24 per 10,000 people [1]. Onset is usually...