Journal Reviews
Fenofibrate and diabetic retinopathy
Fenofibrate is an agonist of peroxisome proliferator-activated receptor-alpha (PPARα) which is used as a lipid-lowering agent. By reducing blood lipid levels, it can decrease retinal hard exudates which is beneficial in diabetic retinopathy (DR). FIELD and ACCORD studies show that...
IVT Aflibercept 2mg in nAMD: XTEND at 3 years
This study investigated the long-term, effectiveness and safety of IVT-AFL 2mg for neovascular age-related macular degeneration (nAMD). XTEND was a multicentre, observational, prospective study, which was conducted across 127 centres across 17 countries with a follow-up period of 36 months....
ILM peeling in proliferative diabetic retinopathy: a meta-analysis
This meta-analysis highlights the efficacy of internal limiting membrane (ILM) peeling on treating posterior segment complications other than macular oedema in patients with proliferative diabetic retinopathy (PDR) treated with vitrectomy. PubMed, EMBASE and Cochrane Library were searched for databases. Eleven...
Conservative vs surgical management outcomes for congenital fibrovascular pupillary membrane for young vs older children
The authors present the clinical characteristics and outcomes of different treatment methods for congenital fibrovascular pupillary membrane (CFPM). This was a retrospective case series from a single centre including 12 patients (13 eyes; 4 males, 8 females) over a 7-year...
Accuracy of ChatGPT responses for questions about strabismus
This study aimed to assess the medical accuracy and readability of responses provided by ChatGPT in relation to patient/parent queries about strabismus. The authors compared responses from the free version (Chat 3.5) with those from a subscription service (version 4.0)....
BTA as a first-line treatment option for acute acquired comitant esotropia
This study presents results of a single-centre institute use of botulinum toxin A (BTA) as an initial treatment choice for acute acquired comitant esotropia (AACE). This was a prospective observational case series study of 72 patients (49 male, 23 female)...
Comparison of degradation of stereoacuity with reduced visual input
The aim of this study was to investigate the differing extents to which stereo thresholds obtained with Frisby, TNO, Lang Stereopad and ASTEROID stereo tests are affected by changes in visual input in adults. Bangerter foils (0.2 and 0.4) were...
Ocular sequalae of spinal muscular atrophy
he authors present a retrospective single-centre cohort study of patients with spinal muscular atrophy – a neurodegenerative disorder presenting between infancy and early adulthood. Forty-eight patients were included in total, with roughly equal numbers of types 1, 2 and 3...
Care of central and branch retinal artery occlusion by optometrists
A survey was distributed to all optometric members of the American Academy of Optometry and the American Optometric Association. Optometric trainees were excluded. The survey comprised of 7 questions covering practice details, proximity to a stroke centre, frequency of diagnosing...
Testing periods for accommodative and vergence facilities
The authors investigate if there is a significant difference in the number of cycles between the first and second 30-second (FASTS) periods of testing accommodative facility and vergence facility, and explore the possibility of reducing testing time by half. The...
Literature review of aspects relating to topical anaesthesia for strabismus surgery
This review was undertaken to consider the benefits and limitations, the nuances in surgical techniques and the preoperative testing and counselling in patients considered suitable for topical anaesthesia strabismus surgery. Preoperative considerations were reported as age, tolerance of forced duction...
Prism fusional vergence measures for Risley vs prism bar measurements
This study sought to investigate the agreement between the phoropter Risley and the prism bar prism fusional vergence amplitudes among a normal sample of Ghanaian children aged 8–17 years. This was a school-based study of 2300 children. Of 2300, 116...
