Two-year results of a T&E aflibercept regime in caucasian PNV

This a retrospective study examining two-year outcomes of patients with pachychoroid neovasculopathy (PNV) treated with a treat and extend (T&E) regimen of intravitreal aflibercept. The mean age was 63.84 ± 7.92 years with nine males (35%) and 17 females (65%)....

Changing operating room practices: the effect on postoperative endophthalmitis rates following cataract surgery

This is a retrospective clinical registry study from India of 85,552 cataract surgery patients; group 1 (56,551 patients from January-March 2020) and group 2 (29,011 patients from May-August 2020). Group 1’s patients were ungowned, surgical gloves were disinfected but not...

Multidrug-resistant keratitis: challenging yet manageable

This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...

Ocular findings in children with myasthenia

This is a retrospective audit of paediatric myasthenic patients presenting to Great Ormond Street (GOSH) between January 2016 and January 2020. During this period there were 49 children, including 27 with juvenile myasthenia (JMG) and the rest as congenital myasthenia...

Macular measurements for amblyopic eyes

This study aimed to evaluate the macular parameters including foveal avascular zone (FAV) size and vessel density in amblyopia vs fellow eyes. The study included 23 unilateral amblyopia children (9.86 ±3.12 years; 52.2% female) and non-amblyopia control eyes (8.67 ±2.06...

Superior oblique sagittalisation

This paper reports two cases with anomalous posterior course of the superior oblique tendon with insertion nasal to the superior rectus tendon. Both presented with Brown syndrome-like clinical scenarios. The cases were a five-year-old female and four-year-old male. Diagnosis was...

Disc-fovea angle measurements for objective cyclotorsion review

The author measured the disc-fovea angle (DFA) in 249 healthy people (81 male, 168 female) as part of a retrospective study of 44 to 70-year-old adults. These were grouped as (1) aged 44 / 45 years, (2) aged 59-70 years,...

Ocular motility parameters in phakic and pseudophakic older people

The aim of this study was to compare the extent of phoria, strabismus and convergence of pseudophakic vs phakic people in an elderly population. The study was part of the Tehran Geriatric Eye Study (TGES). Of 3791 invitees, 3310 participated...

Does Duane syndrome have an effect on refractive error?

The authors present a retrospective case review from a database created from a 43-year period of patients with strabismus seen by a single ophthalmologist. Cases were reviewed by either an orthoptist or ophthalmologist for entry into the database. Details relating...

Optic disc pit maculopathy: an optical coherence tomography study

This was a single-centre, retrospective observational case series that aimed to analyse the change of optical coherence tomography (OCT) characteristics in the natural course of optic disc pit maculopathy (ODP-M) and their effects on visual acuity. Twenty-two eyes of 22...

Patient reported outcomes in adolescents with inherited retinal diseases

This was a two-centre validation study of two sets of patient reported outcome measures (PROMS) for adolescents (13-17- years-old) with inherited retinal diseases. The measures were the Michigan Retinal Degeneration Questionnaire (MRDQ) and the Michigan Vision-Related Anxiety Questionnaire (MVAQ). Both...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...