Journal Reviews
Combined phacoemulsification and hydrus microstent for normal tension glaucoma
This retrospective multicentre study followed up 77 normal tension glaucoma (NTG) eyes undergoing phacoemulsification and Hydrus implantation between 2014 and 2023 over a 36-month period. Primary outcomes were changes in intraocular pressure (IOP) and medication burden, and cumulative success probabilities...
Quality and readability of English and Spanish patient educational materials generated by AI
This study evaluated the quality and readability of ChatGPT-generated patient educational materials for 4 common paediatric ophthalmology procedures, in both English and Spanish languages. Responses were compared to the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) patient handouts. The...
Long-term risk calculation of retinal detachment in childhood myopia
The aim was to examine the risk of retinal detachment in children with myopia over a 10-year follow-up period. This was a retrospective cohort study using the TriNet X platform which houses anonymised electronic patient records from 180 healthcare groups....
Children profile of endogenous endophthalmitis in Vietnam
A retrospective study was conducted to investigate the cause, clinical characteristics and treatment outcomes of paediatric endogenous endophthalmitis in Vietnam. The study included 157 patients (53% male) with mean age of 6.0 ±3.8 years. Average duration from symptom onset to...
Factors associated with presence of stereopsis in early treatment of refractive esotropia
The authors investigate the factors affecting better stereopsis outcomes in 29 patients with refractive accommodative esotropia with an age of onset within 6 months of life who were successfully treated. The study included 17 males and 12 females with mean...
Clinical characteristics of AACE
In this study, the authors aimed to categorise the demographics and clinical characteristics and medical evaluation results in patients with adult acute onset comitant esotropia (AACE). This was a retrospective study of 268 patients; 62.7% female, 84% white, with mean...
The evolving landscape of diabetic retinopathy
This article outlines efforts to modernise clinically meaningful staging systems and endpoints for diabetic retinal disease (DRD). During a workshop involving over 100 international experts, participants emphasised the need for validated structural and functional endpoints based on the retinal neurovascular...
Limitations of next generation sequencing
This is a report of a young female patient with clinically diagnosed retinitis pigmentosa who underwent genetic testing using an inherited retinal disease panel and whole exome sequencing by next generation sequencing (NGS) technology. This approach did not identify any...
Two-year GATHER2 data: anatomical gains, functional questions for avacincaptad pegol in geographic atrophy
Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) remains a leading cause of irreversible central vision loss, and complement dysregulation has long been implicated in its pathogenesis. In 2023, the US FDA approved the first two GA therapies, both...
ROCK inhibition after descemetorhexis without endothelial keratoplasty: a small but timely Indian RCT
The authors present a single-centre, prospective, randomised, comparative clinical trial (RCT) of 24 eyes of 24 patients with mild-to-moderate Fuchs endothelial corneal dystrophy (FECD) undergoing combined phacoemulsification and a standardised 4mm central descemetorhexis without endothelial keratoplasty (DWEK), with or without...
Seeing mitochondrial disease
This review highlights mitochondrial diseases as the most common inherited neurometabolic disorders, often affecting multiple high-energy organs, with eye involvement frequently representing the earliest or predominant feature. Diagnosis is challenging due to significant genetic and clinical heterogeneity, including variable expressivity,...
Healthcare access gaps in adults with vision difficulty
The authors analyse data from the Behavioral Risk Factor Surveillance System (2019–2021) to evaluate disparities in healthcare access among adults with self-reported vision difficulty. This large cross-sectional study demonstrates that individuals reporting visual impairment face significant barriers across multiple domains...
