Journal Reviews
Pain control during orbital implant surgery
This is a study based on existing evidence that pre-emptive pain control has advantages over traditional post-surgical analgesia. The authors compared pain scores in three groups of randomly assigned and masked patients all undergoing orbital implant surgery under general anaesthesia...
Narrative review of idiopathic intracranial hypertension in children / adolescents
Idiopathic intracranial hypertension (IIH) affects both children and adults. Whilst the majority of IIH is mainly seen amongst adults, it also affects children. There are currently no clinical trials in IIH for those who are adolescents or children. The aims...
Agreeing terminology for non-classic visual field abnormalities
The authors present a prospective survey of neuro-ophthalmologists. The survey comprised of 10 visual fields. The selection of visual fields for the survey aimed for variety and excluded classic neuro-ophthalmology visual field defects, e.g. hemianopia, nasal step. The survey was...
Surgical management and review of congenital inferior rectus dysgenesis
Three cases are presented of congenital inferior rectus (IR) dysgenesis causing hypertropia. Case 1 was a two-year-old female with intermittent vertical strabismus of 20PD and -2 limitation on depression, worse in abduction. MRI imaging showed a hypoplastic IR. Following surgery,...
Brolucizumab in age-related macular degeneration, HAWK Study
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...
Proof of concept for using aqueous humour to detect retinoblastoma variant
A proof of concept study is presented with the aim of assessing the feasibility of using aqueous humour surrogate marker for tumour tissue for identifying retinoblastoma RB1 variant. Three children undergoing enucleation for retinoblastoma were recruited from a single centre....
Long-term improvement of stereopsis in intermittent refractive esotropia
This was a retrospective study to review the records of patients with refractive accommodative esotropia (RAET) to determine long-term stereoacuity (SA) improvement in those that showed initial poor or no stereopsis. The study included 79 patients; 54% male and mean...
ROP risk factors
The purpose of this study was to evaluate the incidence and risk factors for retinopathy of prematurity (ROP) in two neo-natal units, and included a sub-analysis of infants with gestational age (GA) of ≥28 weeks. A retrospective review was undertaken...
Outcomes of adult new-onset strabismus presenting acutely
This study evaluated causes, neuroimaging rates and results, and clinical courses of adults presenting to an ophthalmology emergency department with diagnosis of new-onset strabismus. This was a retrospective study of 557 adults (54.8% male) with mean age of 57.3 ±16.7...
Significant associations to presence of significant retinal haemorrhages in suspected child abuse
The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...
Effect of heredity on risk of diabetic retinopathy
This study used survival analysis on 2199 patients who had reached vision-threatening diabetic retinopathy to investigate the contribution of heredity to diabetes together with other known risk factors for the development of either proliferative diabetic retinopathy (PDR) or diabetic macular...
Rare presentation of giant cell arteritis in Chinese subjects
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...
