How the thinking machine is transforming the retinal landscape
1 May 2025
| Zhihang Cheng
|
EYE - Vitreo-Retinal
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...
Long-term treatment for diabetic macular oedema
2 April 2025
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...
Infliximab in treatment of PVR
28 February 2025
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...
Verteporfin shortage: treatment options and outcomes in chronic non-resolving central serous chorioretinopathy
4 February 2025
| Sofia Rokerya
|
EYE - Vitreo-Retinal
Half-dose photodynamic therapy (HD-PDT) with verteporfin has been the therapy of choice in non-resolving central serous chorioretinopathy lasting longer than four months. Since 2021, a worldwide shortage of verteporfin due to manufacturing issues prompted adjustments in treatment practices. This retrospective,...
Google searches predict pathology after a solar eclipse
4 February 2025
| James Kirkpatrick
|
EYE - Vitreo-Retinal
This light-hearted review identified that the Google search term, ‘my eyes hurt’ was trending on 8 April 2024, coinciding with the exact time when a total solar eclipse passed over the US. They identified the subregions that searched this term...
Efficacy and safety of intravitreal faricimab in nAMD, DME and RVO
30 January 2025
| Sofia Rokerya
|
EYE - Vitreo-Retinal
This paper is an analysis of data extracted from 13 eligible studies in the context of neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO), collected from systematic literature search of MEDLINE, Embase, and Cochrane...
Impact of solar eclipses on vision
4 December 2024
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
Solar retinopathy occurs as a result of mechanical and photochemical damage to the retina caused by exposure to excessive light. The authors presented the optical coherence tomography (OCT) and OCT-angiography findings of five patients who looked at the solar eclipse...
Chandelier-assisted versus standard scleral buckling for rhegmatogenous retinal detachment repair. Systematic review and meta-analysis
4 December 2024
| Sofia Rokerya
|
EYE - Vitreo-Retinal
Despite a significant global decline in standard scleral buckling (SSB) procedures for rhegmatogenous retinal detachment (RRD), it continues to hold its place as an essential treatment option, offering distinct advantages such as cost-effectiveness, preservation of the vitreous, improved final visual...
PAX6 methylation and myopia
2 December 2024
| Ian Reekie
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EYE - Vitreo-Retinal
The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...
Update: Non-infectious retinal vasculitis
2 December 2024
| Sofia Rokerya
|
EYE - Vitreo-Retinal
This review article summarises the update on non-infectious retinal vasculitis (RV). It is primarily classified based on the type of retinal vessels involved and further sub-classified as occlusive or nonocclusive. Clinically it can occur as an isolated ocular entity or...
ILM peeling techniques in myopic traction maculopathy
29 November 2024
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
Myopic traction maculopathy (MTM) is a sight-threatening complication of high myopia including macular retinoschisis (MRS) or foveoschisis, foveal detachment (FD) and myopic macular hole (MMH). Standard surgical treatment is vitrectomy with internal limiting membrane (ILM) peeling, but full-thickness macular hole...
Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs
1 November 2024
| Sofia Rokerya
|
EYE - Vitreo-Retinal
The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...
