Journal Reviews
AI-Based devices in national screening programmes: barriers and challenges
Diabetic retinopathy (DR) may have long-term complications and is recorded as a leading cause of blindness. National DR screening programmes have effectively reduced severe visual loss by timely detection and subsequent treatment of sight-threatening proliferative DR and diabetic macular oedema....
Intravitreal Aflibercept (IVT-AFL): treatment of macular oedema secondary to RVO
This paper is a sub-group analysis of the real-world effectiveness, treatment patterns, and safety of IVT-AFL in patients with macular oedema secondary to retinal vein occlusion (RVO) in Italy. One hundred and fifity-two treatment-naïve and 50 pretreated patients were enrolled...
Understanding the pachychoroid disease spectrum
This article provides a comprehensive review of the pachychoroid disease spectrum, a group of chorioretinal disorders characterised by abnormal choroidal thickening and various pathological changes in the choroid, retinal pigment epithelium, and retina. It also highlights the controversies and knowledge...
Outcomes in intermediate age-related macular degeneration (AMD): A MACUSTAR study report
Intermediate AMD (iAMD) is the most high-risk AMD stage for progressing to late AMD. This article gives the report of the MACUSTAR study. A wide range of assessments were conducted across 20 sites in seven European countries, in accordance with...
Reproductive counselling for females with X-linked inherited retinal diseases
The authors report a survey-based study of 118 female patients who were genetically confirmed carriers or obligate carriers of an X-linked inherited retinal disease. The majority (66.9%) of these patients were carriers of choroideremia; other diagnoses included retinitis pigmentosa, X-linked...
Let the eye be the window to your body
The authors offer a comprehensive overview of how the eye provides novel insights into systemic health. The interplay between the eye and body has given rise to the field of oculomics – the application of ophthalmic biomarkers to understand mechanisms,...
Nystagmus in infants (0–1 year)
This article from a tertiary hospital in Jerusalem documents the examination and investigations of 147 infants aged 0–1 years with nystagmus. The most common pathologies were albinism (59%) and inherited retinal dystrophy (IRD) (21%). They had eight patients with vertical...
Changes in ocular biomarkers in Vogt-Koyanagi-Harada disease after pulse steroid therapy
This retrospective study aimed to evaluate the early and chronological changes in ocular biomarkers in patients of Vogt Koyanagi Harada (VKH) disease who received pulse steroid therapy. It further aimed to identify which biomarkers correlated with the best corrected visual...
Anti-VEGF agents treatment outcomes in macular telangiectasia
This article is a review of a systematic literature search on Ovid MEDLINE, Embase, and Cochrane Library, from inception to June 2024 for comparative studies on anti-VEGF agents in macular telangiectasia (MacTel). The primary outcome was the change in best-corrected...
Characteristics of central serous chorioretinopathy by age
The authors present a cohort study of 326 patients with simple central serous chorioretinopathy (CSC) according to the classification system laid down by Chhablani, et al. in 2020. Genotyping for two variants of the CFH gene rs800292 and rs1329428 was...
Associations between cerebral vascular malformations and retinal venous malformations
The authors present a retrospective medical notes review which aimed to understand associations between retinal venous malformations (RVM) and cerebral vascular malformations (CVM). Cases of known CVM over a four-year period were identified. The data extracted from medical records included...
Risk for systemic hypertension in ROP with IVB or laser therapy
The purpose of this study was to investigate whether there is an association between intravenous bevacizumab (IVB) and hypertension among infants with severe retinopathy of prematurity (ROP) and comparing those treated with IVB to those treated with laser, or infants...
