Associations between cerebral vascular malformations and retinal venous malformations
The authors present a retrospective medical notes review which aimed to understand associations between retinal venous malformations (RVM) and cerebral vascular malformations (CVM). Cases of known CVM over a four-year period were identified. The data extracted from medical records included...
Risk for systemic hypertension in ROP with IVB or laser therapy
The purpose of this study was to investigate whether there is an association between intravenous bevacizumab (IVB) and hypertension among infants with severe retinopathy of prematurity (ROP) and comparing those treated with IVB to those treated with laser, or infants...
Reattachment rate with pneumatic retinopexy vs pars plana vitrectomy for single break rhegmatogenous retinal detachment
This is a post-hoc analysis of two clinical trials, including patients who underwent pneumatic retinopexy (PnR) vs pars plana vitrectomy (PPV) and had met the management of primary rhegmatogenous retinal detachment outcomes randomised trial (PIVOT) criteria with a single break...
Vascular density evaluated by SS-OCTA and microperimetry in RP
The aim of this retrospective, observational cross-sectional one-year study was to evaluate the retinal and choroidal vessel density in the macular area with swept-source optical coherence tomography angiography (SS-OCTA) in patients of retinitis pigmentosa (RP), to compare this data with...
Results of vitrectomy in epiretinal membranes secondary to retinal vein occlusions
This retrospective, observational multicentre study investigated the anatomic and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes. Data was collected...
Posner-Schlossman Syndrome (PSS) European Study Group: study protocol and baseline patient characteristics of a multicentre study
This is a retrospective, multicentre (11 centres) study of European patients (total 107; Caucasians in 93.4%). Age ranged between 11 and 76 years with mean age 42 ±15 years. Best corrected vision was >0.5logMAR in 80.3% of the eyes, and...
Choroideremia in women
The authors report a questionnaire-based study of female carriers of choroideremia, an X-linked inherited chorioretinal dystrophy. As an X-linked condition the full clinical features are predominantly seen in men but a proportion of women suffer some morbidity, likely due to...
Macular characteristics in unilateral idiopathic FTMH and fellow eyes
This retrospective observational study, conducted at a single site, aimed to compare characteristics of the macular structure and foveal pit in unilateral full-thickness macular hole (FTMH) and healthy fellow eyes. Full-thickness macular holes were further classified into three categories: (1)...
EDOF intraocular lens in eyes with preexisting retinal disease
Extended depth of focus (EDOF) intraocular lens (IOL) offers improved near and intermediate vision, aiming to reduce spectacle dependence in cataract patients. This study aims to evaluate the performance of EDOF lenses following cataract surgery in patients with retinal pathology....
How the thinking machine is transforming the retinal landscape
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...
Long-term treatment for diabetic macular oedema
The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...
Infliximab in treatment of PVR
In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...