Journal Reviews
Long-term comparative outcomes of Hydrus versus iStent inject microinvasive glaucoma surgery implants combined with cataract surgery
This was a retrospective study of 429 eyes (98 phaco-Hydrus (HD), 331 phaco-iStent (IS)) in the overall cohort and 177 eyes (59 phaco-HD, 118 phaco-IS) in the matched cohort over a 48-month period. There was no significant difference in surgical...
Incidence of high IOP following corneal collagen cross-linking
This retrospective cohort study examined 405 patients (405 index eyes and 218 untreated fellow eyes) who underwent cross-linking over a 12-year follow-up duration at Duke Eye Center. Preoperative and postoperative intraocular pressure (IOP) measurements were collected at ~1 month, 3...
Risk factors for ocular complications following orbital fractures
In this Japanese retrospective cohort study, the authors examined records of 416 consecutive orbital fracture patients treated over a 10-year period at a single institution. The study identified ocular complications occurring in 9.5% of the cases, with traumatic mydriasis, hyphaemia...
Pneumatic trabeculectomy
The authors present a novel technique which uses constant pressure air infusion via the constellation vision system (Alcon Laboratories) to prevent anterior chamber (AC) collapse and intraocular pressure fluctuations during trabeculectomy in high-risk cases. This was a prospective, interventional, non-randomised,...
Care of central and branch retinal artery occlusion by optometrists
A survey was distributed to all optometric members of the American Academy of Optometry and the American Optometric Association. Optometric trainees were excluded. The survey comprised of 7 questions covering practice details, proximity to a stroke centre, frequency of diagnosing...
Opening the AI ‘black box’ for glaucoma
Artificial intelligence (AI) models show great promise for glaucoma detection using retinal images, but their ‘black box’ nature is a major barrier to clinical adoption. Clinicians are often hesitant to trust a diagnosis without understanding its reasoning. This paper provides...
Low-dose bimatoprost/timolol gel: a new fixed-combination option
This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...
Selective laser trabeculoplasty after medical treatment
Selective laser trabeculoplasty (SLT) is a well-established treatment for open-angle glaucoma (OAG) and ocular hypertension (OHT). This post-hoc secondary analysis of the LiGHT trial extension examined SLT as a secondary intervention after 3 years of protocolised medical therapy in patients...
Risk of fractures with glaucoma
In this systematic review and meta-analysis, 7 articles were analysed, with 570,694 subjects and a reported total of 45,957 fractures. The study protocol (CRD42024527785) was registered prospectively. PubMed, EMBASE, and Web of Science were searched from their inception to April...
Clinical outcomes following intraluminal stent removal from the PAUL glaucoma implant
This single German centre retrospective cohort study included 70 eyes from 68 patients. Qualified and complete success rates (95% CI) were 92.9% and 55.7% after 1 year and 88.6% (81.4–95.7%) and 50% (37.1–62.9%) at the last follow-up time point for...
Understanding optic nerve head pericytes and glaucoma
The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...
Feasibility and acceptability of virtual reality visual field testing compared to standard perimetry
The authors present a prospective pilot study which aimed to assess the feasibility and performance of the vivid vision perimeter (VVP). The VVP is a piece of software which can be used with off-the-shelf virtual reality (VR) headsets. Recruitment took...
