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Somatostatin protects retinal pericytes

Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...

A case presentation of morning glory disc anomaly and peripapillary staphyloma

The purpose of this paper is to present a case of an 18-month-old girl initially presenting with strabismus. Fixation of the affected eye was intermittent with a relative afferent pupillary defect. A fundus photography of the affected left eye showed...

Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

Lothian Optometry Teach and Treat Clinic

The Lothian Optometry Teach and Treat (LOTT) Clinic is a supervised training clinic for community optometrists with an interest in managing patients with acute eye pathology, normally managed in the hospital setting. LOTT, which is the first clinic of its...

Diagnoses of dry eye disease double within a year

Over a third of Britons haven’t had an eye test within the last two years, while one in five have not had an eye test due to financial struggles.

Forward-tilt technique for intraocular pressure measurement in upgaze

The authors suggest a technique to improve the accuracy of measuring IOP in upgaze using Goldmann applanation tonometry. Graves’ ophthalmopathy, also known as thyroid eye disease, is an autoimmune inflammatory condition affecting the orbit and periorbital tissues [1]. It was...

BIOS: Clinical Tutor Course

British and Irish Orthoptic Society

RSM: Modern Ophthalmology: Students, Residents and MDT Conference

Royal Society of Medicine: Modern Ophthalmology: Students, Residents and MDT Conference

Atlas of Clinical and Surgical Orbital Anatomy (Third Edition)

This textbook highlights in its preface to the third edition that considerable research has been undertaken in the fields of orbital and periorbital anatomy since 1994 (first edition) and 2011 (second edition). Various topics have been elucidated, such as the...

How does cataract surgery affect eyes with wet AMD?

In this retrospective cohort study the authors’ primary objective was to assess whether cataract surgery in eyes with wet age-related macular degeneration (AMD), triggered its progression. The surgical group comprised of 40 eyes versus 42 eyes in the non-surgical control...

OCTA in diabetic macular oedema treated with intravitreal aflibercept (DOCTA Study)

Central vision loss due to diabetic macular oedema (DME) can be attributed not only to presence of the macular oedema itself but also, in some cases, to alterations of the foveal avascular zone (FAZ). The DOCTA trial was a longitudinal,...