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Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Lessons from an unusual case of syphilis

The rise of syphilis transmission rates over the past two decades has been one of public health’s great puzzles. In the UK, the situation has reached epidemic levels, with a 126% increase between 2013 and 2018 [1]. We present a...

Ophthalmic Imaging: From Theory to current practice

Welcome to the 14th edition of the Ophthalmic Imaging Congress. This event, focused on Imaging and all its applications in ophthalmology, will allow us to reflect on the technological advances and the progress we have made. Program: - Theoretical Sessions:...

ARVO (The Association for Research in Vision and Ophthalmology) 2025

i3: imagining innovation and intelligence in vision science This is an incredibly exciting time in ophthalmology and vision science research. Technological innovations have allowed us to probe the workings of the eye from the microscopic to the macroscopic level with...

The approach to trabeculectomy postoperative complications

Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...

The symbolism of eyes in Halloween traditions and popular culture

Halloween is a festival steeped in symbolism. Pumpkins, skeletons, ghosts and witches dominate the seasonal iconography, each representing broader cultural anxieties about death, darkness and the supernatural. Among these motifs, the eye, often depicted as glowing, disembodied or grotesquely exaggerated,...

Suspected vitreous seeding of uveal melanoma

This is a retrospective non-randomised study of 23 patients with consecutive uveal melanoma who underwent diagnostic vitrectomy between the period of January 2000 and November 2013. The reason for vitrectomy was suspected dissemination of tumour cells inside the eye. The...

Making sense of the orthoptic assessment

Following the Specialty Trainee article on this topic in the February/March 2020 issue, Joe Smith provides a more detailed breakdown of the orthoptic report. Orthoptists investigate, diagnose and manage a wide variety of patients with varying problems. In this article,...

Does modern radiological imaging detect lesions associated with internuclear ophthalmoplegia?

The authors present a retrospective case review including all patients with a diagnosis of internuclear ophthalmoplegia (INO) presenting to two tertiary neuro-ophthalmology centres over a five-year period. The aim of the study was to assess the sensitivity of modern radiological...

What's trending Apr/May 2019

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #JessicaStarr #suicide This Detroit meteorologist committed suicide in December 2018 following SMILE corrective laser refractive surgery back in October 2018. Small...

Atlas of Clinical and Surgical Orbital Anatomy (Third Edition)

This textbook highlights in its preface to the third edition that considerable research has been undertaken in the fields of orbital and periorbital anatomy since 1994 (first edition) and 2011 (second edition). Various topics have been elucidated, such as the...

How to survive the fluorescein round

One of the highlights of the medical retina fellowship programme at Moorfields is the Tuesday morning 8am fluorescein round. It is both exhilarating and terrifying. Exhilarating because they are slick presentations of the most interesting cases that each of the...