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Don’t ignore the black lesion! It might be mucormycosis

Keeping mucormycosis infection in the foreground of your differential diagnosis, especially in those more vulnerable patients, will help save their lives if recognised and managed appropriately. Mucormycosis is a fulminant infection caused by the fungi of the family Mucoraceae. It...

Review of pathogenesis of Acanthamoeba keratitis

In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Lessons from an unusual case of syphilis

The rise of syphilis transmission rates over the past two decades has been one of public health’s great puzzles. In the UK, the situation has reached epidemic levels, with a 126% increase between 2013 and 2018 [1]. We present a...

The approach to trabeculectomy postoperative complications

Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...

The symbolism of eyes in Halloween traditions and popular culture

Halloween is a festival steeped in symbolism. Pumpkins, skeletons, ghosts and witches dominate the seasonal iconography, each representing broader cultural anxieties about death, darkness and the supernatural. Among these motifs, the eye, often depicted as glowing, disembodied or grotesquely exaggerated,...

Suspected vitreous seeding of uveal melanoma

This is a retrospective non-randomised study of 23 patients with consecutive uveal melanoma who underwent diagnostic vitrectomy between the period of January 2000 and November 2013. The reason for vitrectomy was suspected dissemination of tumour cells inside the eye. The...

Making sense of the orthoptic assessment

Following the Specialty Trainee article on this topic in the February/March 2020 issue, Joe Smith provides a more detailed breakdown of the orthoptic report. Orthoptists investigate, diagnose and manage a wide variety of patients with varying problems. In this article,...

Rare case reports of benign optic glioma in adults with clinically aggressive nature

Primary optic nerve gliomas are most commonly benign and occurring in childhood. Malignant optic gliomas occur in adulthood and follow an aggressive course usually leading to blindness and death within months. This paper describes the clinical and histopathological features of...

Does modern radiological imaging detect lesions associated with internuclear ophthalmoplegia?

The authors present a retrospective case review including all patients with a diagnosis of internuclear ophthalmoplegia (INO) presenting to two tertiary neuro-ophthalmology centres over a five-year period. The aim of the study was to assess the sensitivity of modern radiological...

What's trending Apr/May 2019

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #JessicaStarr #suicide This Detroit meteorologist committed suicide in December 2018 following SMILE corrective laser refractive surgery back in October 2018. Small...

How to survive the fluorescein round

One of the highlights of the medical retina fellowship programme at Moorfields is the Tuesday morning 8am fluorescein round. It is both exhilarating and terrifying. Exhilarating because they are slick presentations of the most interesting cases that each of the...