Journal Reviews
Incidence and clinical characteristics of paediatric keratitis
This is a retrospective, population-based study of a 10-year period from Mayo Clinic, USA between January 2000 and December 2009 of patients <19 years diagnosed with keratitis. Two-hundred and eight-five children were identified. An incidence of 78 per 100,000 and...
Correlation between aqueous flare and macular microvascular status in diabetes mellitus
The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...
Treatment of severe chronic ocular graft-versus-host disease
A retrospective study from Cologne, Germany, between November 2012 to March 2015, of 17 patients with graft-versus-host disease (GVHD) treated with 100% single use vials autologous serum eye drops in sealed system. Visual acuity, corneal staining, frequency of artificial tears,...
Clinical outcomes of AMT in acute ocular chemical injury
This is a retrospective study of patients from two units in Germany and UK between 1998 and 2008. The ocular chemical burns were classified by Roper-Hall and Dua classifications. A total of 72 eyes of 54 patients aged 37.3 years...
Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...
Rituximab efficacy for juvenile idiopathic arthritis
This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....
Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...