Incidence and clinical characteristics of paediatric keratitis
2 February 2024
| Jonathan Chan
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EYE - Paediatrics, EYE - Strabismus
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Contact lens, Epidemiology, Inflammation, Vision
This is a retrospective, population-based study of a 10-year period from Mayo Clinic, USA between January 2000 and December 2009 of patients <19 years diagnosed with keratitis. Two-hundred and eight-five children were identified. An incidence of 78 per 100,000 and...
Correlation between aqueous flare and macular microvascular status in diabetes mellitus
7 April 2021
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Aqueous flare, Diabetic retinopathy, Inflammation, Laser flare-cell meter, Microvascular injury, Optic coherence tomography angiography
The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...
Treatment of severe chronic ocular graft-versus-host disease
1 February 2018
| Jonathan Chan
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EYE - Cornea, EYE - General
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Cornea, Inflammation, Treatment Medical, Wound healing
A retrospective study from Cologne, Germany, between November 2012 to March 2015, of 17 patients with graft-versus-host disease (GVHD) treated with 100% single use vials autologous serum eye drops in sealed system. Visual acuity, corneal staining, frequency of artificial tears,...
Clinical outcomes of AMT in acute ocular chemical injury
1 August 2017
| Jonathan Chan
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EYE - Cornea, EYE - General
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Cornea, Inflammation, Ocular surface, Stem Cells, Treatment Surgery
This is a retrospective study of patients from two units in Germany and UK between 1998 and 2008. The ocular chemical burns were classified by Roper-Hall and Dua classifications. A total of 72 eyes of 54 patients aged 37.3 years...
Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)
1 April 2017
| Yamini Krishna
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EYE - Pathology, EYE - Oncology
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Atopia, Inflammation, Masquerade, Neoplasia, Ocular surface
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...
Treatment of Sjogren’s Syndrome dry eye in mouse model
1 April 2016
| Graham Wallace
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EYE - Cornea, EYE - General
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Autoimmune, Chronic, Conjunctiva, Inflammation, Ocular surface, Sjögren's syndrome
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
