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Neuro-Ophthalmology journal cover image

Patterns of binocular diplopia in giant cell arteritis (GCA)

3 February 2023 | | Neuro-Ophthalmology | Diplopia, giant cell arteritis, population-based
Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...

Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

1 December 2014 | | Retina / Uvea / Vitreous
In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Toxic nutritional optic neuropathy (TON)

2 August 2022 | | Ophthalmology
Toxic optic neuropathy are a group of conditions manifested by reduction of visual functions secondary to damage to the anterior visual pathways from exposure to a toxin. The implicated toxin could be work-based, food or drink related, or iatrogenic medication....

On the wrong track

1 June 2015 | | Cataract and Refractive, Imaging, Ophthalmology, Retina / Uvea / Vitreous
A 65-year-old very high myope lady presented with sudden blurred vision down to count fingers to her right eye after a short and sharp pain. She also described seeing a black swirly line and as all these symptoms were exactly...

Dec/Jan 2017 Quiz

1 December 2016 | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, AMD, Emergency Ophthalmology
History An 18-month-old boy presented with a slow growing left anterior orbital lump medially. Examination revealed a palpable mass beneath the skin at the inferonasal aspect without any visual impairment. A CT scan (Figure 1) followed by an excisional biopsy...

Apr/May 2014 Quiz 1

1 April 2014 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Oculoplastics, Ocular Pathology and Oncology, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
History A 45-year-old man presents with left-sided epiphora. During a dacrocystorhinostomy (DCR), the wall of the lacrimal sac was noted to be bulky. The sac wall is biopsied and sent for routine histopathology examination. The pathologist notes a distinctive feature...

Optic nerve swelling – your survival guide (part 1)

1 August 2017 | | Neuro-Ophthalmology
Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

Oct/Nov 2018 Quiz

1 October 2018 | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
History A 37-year-old male was referred from the Emergency Eye Clinic with a swollen right upper eyelid. Symptom relieved with nonsteroidal anti-inflammatory drugs (NSAIDs). The initial clinical diagnosis was dacryoadenitis. The patient presented again six weeks later with 3mm proptosis,...

An unusual presentation of sarcoidosis

1 October 2021 | | Ophthalmology, Retina / Uvea / Vitreous, Imaging, Neuro-Ophthalmology
*Equally contributing co-first authors. Case report A 45-year-old man presented to his local optometrist with a three-week history of severe intermittent left eye pain with associated blurred vision and tenderness around his left temple. Two days prior, he developed weakness...

Optical coherence tomography – reinventing the eye examination

1 October 2016 | | Retina / Uvea / Vitreous, Imaging
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...

It’s not always GCA

7 December 2020 | | Ophthalmology, Neuro-Ophthalmology
Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...

Ciliary body granuloma masquerading as a melanoma

3 February 2023 | | Ophthalmology
Introduction Sarcoidosis is a multisystem granulomatous inflammatory condition which predominantly affects the pulmonary system and intrathoracic lymph nodes, followed by ocular involvement [1]. We present an interesting patient who developed acute anterior uveitis and subsequent ciliary body granuloma clinically mimicking...