Journal Reviews
Predicting outcome for visual acuity in optic neuritis associated with multiple sclerosis
The authors present a retrospective cohort study to evaluate key predictors of long-term high-contrast visual acuity following optic neuritis associated with multiple sclerosis. All patients coded as optic neuropathy and assessed by a neuro-ophthalmologist over a 10-year period were screened...
Acromegaly associated with enlargement of extraocular recti muscles
This retrospective case review aimed to evaluate the frequency and extent of extraocular muscle enlargement in cases of acromegaly at presentation. All new presentations of acromegaly diagnosis at a single tertiary centre over a five-year period were screened for inclusion....
Could idebenone by the solution for treating dominant optic atrophy?
Dominant optic atrophy (DOA) is a disease of the retinal ganglion cells, with no current treatment options. In most cases, DOA is caused by a mutation in the OPA1 gene. The aim of this study was to evaluate the effect...
Longitudinal findings in children with neurofibromatosis type 1
This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...
Portable vision reading device shows promise for low vision after brain injury
The authors report a small sample cohort study evaluating the impact of a portable vision reading device (OrCam Read) on vision-related quality-of-life and independent functional status in patients with low vision due to stroke or brain tumours. Six patients with...
Septo-optic dysplasia – a case note review
Septo-optic dysplasia (SOD) is a congenital disorder belonging to the midline brain malformation group. The condition manifests as a classical triad, including optic nerve hypoplasia (ONH), agenesis of midline structures (absent septum pel-lucidum and agenesis of the corpus callosum), and...
Characteristics of neuro-ophthalmic visual disturbances post-cataract surgery
The authors present a retrospective case review of adult patients seen by neuro-ophthalmology over a nine-year period. The aim of the study was to identify the cause of neuro-ophthalmic referrals within six months of cataract surgery. Individuals already known to...
Tumour characteristics influencing visual field outcomes
This retrospective study aimed to explore correlations between pituitary tumour characteristics which influenced visual field changes. Cases of transsphenoidal surgery from a six-year period resulting in a pathologic diagnosis of pituitary adenoma from a single centre were identified. Individuals were...
Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review
Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...
Comparison of paediatric migraine and healthy controls using optical coherence tomography angiography
The authors present a cross-sectional study which recruited patients with paediatric migraine without aura along with age and sex-matched healthy controls. Both groups were recruited following attendance to an ophthalmology outpatient clinic. Children diagnosed with any of the following were...
Homonymous hemianopia due to stroke presenting symptoms and lesion locations
A retrospective case notes review was undertaken of patients diagnosed with homonymous hemianopia following a radiologically confirmed stroke. A total of 85 patients were identified by searching an electronic medical records system over an 11-year period. Data were extracted from...
Is virtual reality perimetry as reliable as static perimetry in detecting neurological visual field loss?
This study compares agreement between virtual reality perimetry (VRP) and static automated perimetry (SAP) in a variety of neuro-ophthalmological conditions. For this work the Order of Magnitude (OM) VR-based visual field assessment system was used which has been developed by...
