A case study of posterior globe flattening in idiopathic intracranial hypertension

The authors present a single case of posterior globe flattening without papilloedema in idiopathic intracranial hypertension. The case was a 64-year-old woman with a one-year history of transient visual loss in her left eye only. Visual acuity was 20/20 in...

A novel way to diagnose optic neuropathies using Bruch’s membrane opening

Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...

Investigating the effect of signal strength on mean retinal nerve fibre layer

The aim of this study was to determine the effect of signal strength on mean retinal nerve fibre layer (RNFL) using spectralis optical coherence tomography (S-OCT). Thirty normal subjects were imaged with S-OCT using variably dense Bangerter foils to alter...

Investigating MOG-IgG as a cause for optic perineuritis

Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...

Examination of optic disc drusen using computer-based fundus analysis

This case-control study analysed the optic disc angioarchitecture in optic disc drusen (ODD) using computer-based fundus examination. A group of ODD patients were compared to a group of healthy controls with normal optic discs. The cohort included 30 healthy volunteers...

A novel presentation of optic disc oedema with syphilis

Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....

Mechanism of colour vision involvement in multiple sclerosis

There is evidence to show that the optic nerve and retina are affected in multiple sclerosis (MS) even without any clinical evidence or history of optic neuritis (ON). MS without optic neuritis causes colour-vision deficit, however, the evidence for selective...

Using small amplitude saccades to assess saccadic velocity

Saccades are a key component in the assessment and diagnosis of neuro-ophthalmological disorders. Clinicians are typically taught to use large amplitude saccades (LAS) of at least 20 degrees to assess saccadic velocity. It has been suggested, however, that small amplitude...

Saccadic eye movements in young-onset Parkinson’s disease

The objective of this study was to understand control of saccadic eye movements in patients with young onset Parkinson’s disease (YOPD) where onset of disease symptoms appears early in life (<40 years of age). Functional magnetic resonance imaging (fMRI) was...

Long-term treatment of blepharospasm using Botulinum Toxin A

The authors report findings from a retrospective single-centre study which aimed to evaluate the efficacy and safety of long-term botulinum A toxin (BAT) treatment in patients with blepharospasm (BPS). Blepharospasm is described as one of the most frequent types of...

Using video-oculography to record monocular eye movements

The aim of this study was to examine the characteristics of monocular eye movements recorded using video-oculography (VOG). VOG monocular recording has become increasingly popular in comparison to electro-oculographic binocular recording, due to its simple technique. The authors evaluated the...

A case of ipsilateral fourth nerve paresis and Horner’s syndrome

The author presents a single case report of an exceptional association between fourth nerve palsy and ipsilateral Horner’s Syndrome. The case is presented alongside magnetic resonance images (MRI) which reveal a mass in the right cavernous sinus. The 54-year-old woman...