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21st Century retinal laser treatment in the anti-VEGF era

1 June 2017 | | Retina / Uvea / Vitreous
In today’s world, macular laser treatment has a vital role in the treatment of diabetic macular oedema (DMO). DMO is one of the most common causes of visual impairment. Despite expensive intravitreal treatment courses of anti-VEGF, many will agree that...

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

5 April 2022 | | Neuro-Ophthalmology | Neuro-ophthalmology, moyamoya vasculopathy, optical coherence tomography angiography, retina
Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

The role of injection assistant devices in establishing a nurse-led AMD service

1 April 2018 | | Retina / Uvea / Vitreous
The author shares his experience of setting up a nurse-led service to deliver anti-VEGF intravitreal injections and how injection assistant devices supported training. Age-related macular degeneration (AMD) has become a leading cause of irreversible blindness [1]. It is estimated that...

More sensitive visual acuity test for age-related macular degeneration

1 October 2016 | | Retina / Uvea / Vitreous
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

1 October 2015 | | Retina / Uvea / Vitreous
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...
Ophthalmologica journal cover image

Assessment of retinal capillary VD and FAZ area in CSC using OCTA

7 April 2021 | | Retina / Uvea / Vitreous | Central serous chorioretinopathy, Optical coherence tomography, Optical coherence tomography angiography, Visual acuity
The authors aim to report a cross-sectional, case controlled study, the purpose of which was to access the retinal capillary vessel density (VD) and foveal avascular zone (FAZ) area in acute and chronic central serous chorioretinopathy (CSC) patients compared to...

NICE drugs: an update on what’s good to go

1 June 2014 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Treatment options recommended by the National Institute for Health and Care Excellence (NICE) must be readily available for use in the NHS of England and Wales. This article provides an overview of recent guidance from NICE and summary advice issued...

Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management

1 December 2016 | | Retina / Uvea / Vitreous
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...

Discussing treatment modalities for bilateral wet AMD

1 December 2014 | | Retina / Uvea / Vitreous
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | Ophthalmology, Retina / Uvea / Vitreous
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Screening for Sickle Cell Retinopathy (SCR): Why we do wide-field imaging, OCT/OCT-A for SCR – Newcastle upon Tyne Hospitals NHS Foundation Trust

1 June 2022 | | Retina / Uvea / Vitreous, Imaging
I have been working in ophthalmology for over five years as a photographer and research co-ordinator, and it is fascinating, rewarding, and interesting to learn all about the different diseases associated with the eye. One condition that has been a...

A near miss

1 February 2019 | | Ophthalmology, Retina / Uvea / Vitreous
A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...