Journal Reviews
Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity
Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...
A paradigm shift: re-defining success in retinal detachment repair
The authors describe in this review article that functional outcomes vary with surgical technique for retinal detachment repair. Traditional definitions of surgical success have been shifted due to advances in imaging techniques. Assessment of the integrity of retinal reattachment including...
Does paediatric rhegmatogenous retinal detachment (RRD) obey Lincoff’s rule (LR)?
This was a retrospective study where 98 paediatric patients with RRD were identified through surgery records. Forty case sheets with complete record of ocular examination and surgical findings were analysed. Visible or suspected preoperative retinal break identified using the LR...
Treatment outcomes for retinal detachment
This is a retrospective, nationwide, multicentre study with retinal detachment (RD) in the Japan-RD registry between 2016 to 2017. The primary outcome was the estimated mean difference of postoperative corrected visual acuity (CVA) in six months and a propensity score...
Chorioretinal atrophy in punctate inner choroidopathy / multifocal choroiditis
This study reported the five-year outcomes of chorioretinal atrophy (CRA) progression in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) in 45 eyes of 36 patients. The mean age of the cohort of patients was 37 ±13.37 years...
Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis
Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...
Efficacy of combined vitrectomy with intravitreal corticosteroid injection for ERM
In this study the authors evaluated the efficacy of vitrectomy combined with corticosteroid injection for idiopathic epiretinal membrane (ERM). A systematic literature review was conducted by searching three electronic databases, PubMed, Embase and Medline, up to 2020 for relevant studies....
Impact of COVID-19 on primary retinal detachments
This study aimed to describe the impact of the COVID-19 pandemic on the presentation characteristics, timings, and surgical decisions for primary rhegmatogenous retinal detachment (RRD). The cohort included all patients who presented to a Portuguese centre over a two-year period,...
Air tamponade in pars plana vitrectomy for primary rhegmatogenous retinal detachment repair
The authors report a study aimed to establish the use of air as a tamponade agent for primary rhegmatogenous retinal detachment (RRD) treatment, regardless of the position or the number of retinal breaks. Two hundred and thirty-six eyes of 230...
Using optical coherence tomography angiography to detect MoyaMoya vasculopathy
Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...
Cystoid macular oedema following retinal detachment surgery
There are limited studies examining the incidence and risk factors for postoperative cystoid macular oedema (CMO) following rhegmatogenous retinal detachment (RRD) repair. Postoperative CMO is thought to be due to pro-inflammatory state, where numerous cytokines lead to tight junction dysfunction,...
Occult central retinal artery occlusion
Central retinal artery occlusion (CRAO) is a sight-threatening condition resulting from occlusion of the central retinal artery and hypoperfusion of the inner retina. Early on, fundal examination may be normal. The authors present a retrospective case series of 11 patients...
