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PACK-crosslinking for infectious keratitis

1 October 2015 | | EYE - Cornea
Corneal cross-linking with riboflavin and UV-A light (CXL) is a technology that has been initially developed to treat corneal ectatic disorders [1]. Its effect in stabilising diseases such as keratoconus was reported in numerous trials with excellent long-term outcomes and...

Assessing everyday visual function in dry AMD – what matters to the person?

1 April 2019 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the primary cause of blindness in the developed world and is accountable for more than one half of sight impairment registrations within England and Wales [1]. AMD is prevalent in people aged 60 years and...

Retinal prosthetics: science fiction or a vision for the future?

2 December 2019 | | EYE - Vitreo-Retinal, EYE - General
“Is it a fact – or have I dreamt it – that, by means of electricity, the world of matter has become a great nerve, vibrating thousands of miles in a breathless point of time?” – Nathaniel Hawthorne, The House...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Sustainability in eyecare: Intraocular gases and the climate emergency

4 August 2021 | | EYE - Vitreo-Retinal, EYE - General
In 2020 the NHS became the first national health system to commit to delivering ‘net zero’ carbon emissions by 2040. The author investigates how the impact of ophthalmic surgery can be reduced. Medical gases have been used in ophthalmic surgery...

Two cases of acute syphilitic posterior placoid chorioretinitis

4 December 2025 | | EYE - Imaging, EYE - Vitreo-Retinal
Syphilis has re-emerged as a significant public health concern, with the World Health Organization (WHO) estimating that 8 million adults aged 15–49 acquired syphilis in 2022. Untreated syphilis can have severe consequences, including cardiovascular, neurological and ocular complications. Ocular manifestations...

OCT in neuro-ophthalmology: A practical overview

5 August 2026 | | EYE - Imaging, EYE - Neuro-ophthalmology
From multiple sclerosis to raised intracranial pressure, optical coherence tomography is transforming how we diagnose, monitor and predict outcomes across the full spectrum of neuro-ophthalmic disease. Optical coherence tomography (OCT) is a rapid imaging method that utilises light waves to...

Managing a dislocated intraocular lens

1 October 2014 | | EYE - Cataract, EYE - Refractive
A 70-year-old male patient is referred from the optician with a history of onset of double vision and examination shows a dislocated / subluxated IOL. How will you manage this patient? If the double vision is causing serious concern to...

The results of the last survey Apr21

6 April 2021 | | EYE - Cataract, EYE - Refractive, EYE - General
There was a really fascinating response to the last edition’s practice variance survey. Strictly speaking, I cheated and this was not really about practice variation, but more about your impressions about what represents negligent practice. For the first time ever,...

Cytomegalovirus retinitis post intravitreal triamcinolone in an immunocompetent patient with juvenile glaucoma

1 December 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Figure 1: Fundus photograph shows active CMV retinitis four weeks after IVTA in the right eye. Figure 2: Fundus photograph of the left eye with no CMV retinitis; atrophic disc as a result of juvenile glaucoma. Case report A 29-year-old...

Clinical and management strategies in glaucoma practice: perspectives from international glaucoma specialists

1 April 2015 | | EYE - Glaucoma
Management options and outcomes in glaucoma practice were reviewed at the 7th Moorfields International Glaucoma Symposium, held in London on 24 January 2015. This article summarises perspectives from international glaucoma specialists on debated issues in topical therapy, glaucoma surgery, diagnostic...

Feb/Mar 2018 Quiz

1 February 2018 | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 48-year-old farmer with gradual worsening vision in her only eye was referred by her optician. She had recently moved to the UK and required an interpreter during consultation. She seemed to have had vision problems since childhood. Although...