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What’s new in glaucoma? Clinical trials drive practice changes, surgical advancements gather pace
Rod McNeil reviews the latest developments in the treatment of glaucoma in the UK. Primary open-angle glaucoma (POAG), which accounts for over two-thirds of all glaucoma cases, has an estimated UK prevalence in 2017 of approximately 2% of people over...
Conjunctival mapping biopsies in sebaceous carcinoma
This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...
Imiquimod for lentigo maligna
This is a retrospective review of 12 patients with periocular lentigo maligna treated with topical 5% imiquimod cream. In six patients it was the only treatment, and in the other six it was used following partial excision, cryotherapy or both....
Long-term outcomes following surgery for traumatic cyclodialysis clefts
1 April 2014
| Nana Theodorou
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EYE - General
This retrospective case series evaluated the long-term visual prognosis and intraocular pressure control following surgical treatment of traumatic cyclodialysis clefts. Cyclodialysis clefts result from the disinsertion of the longitudinal ciliary muscle fibres from the scleral spur and occur as a...
Periocular sweat gland carcinomas
This is an interesting review of a rare group of tumours which together comprise the adnexal sweat gland carcinomas. Although there are only 22 patients, this is the largest cohort ever published. The authors summarise the clinical presentation, stage, management...A patient report of pseudoxanthoma elasticum, angioid streaks and choroidal neovascularisation
1 October 2015
| Zaria Ali, Mohammed Alarbi, Salwa Abugreen
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EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) on their own do not cause many problems, with the majority of patients remaining asymptomatic [1]. However, once choroidal neovascularisation (CNV) occurs, the visual prognosis of the patient rapidly declines [2]. Treatment is imperative to try and...
Strange Sequelae Succeeding ‘Surfer’s Eye’
1 February 2014
| Jonathan Park
Ophthalmologists in the UK are relatively infrequently faced with a patient requesting surgery for a pterygium. This condition is more common where ultraviolet exposure is greater, especially if coupled with activities associated with ocular surface irritation. For this reason, a...
Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)
3 April 2023
| Li Yen Goh
Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...
Acute retinal necrosis presumably caused by Epstein-Barr virus infection
1 October 2015
| Antigoni Koukkoulli, Mark Cachia Markman, Anindita Homchoudhury, Oliver Backhouse
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EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Acute retinal necrosis (ARN) is an uncommon, but serious and potentially blinding condition. ARN is characterised by panuveitis, occlusive vasculopathy and progressive peripheral necrotising retinitis. The diagnosis is clinical but confirmation is sought via aqueous and vitreous sampling. Varicella zoster...
Ocular electrophysiology
A 34-year-old woman, who is a CEO in a multinational firm, has been losing vision over the last 12 months. She has seen her opticians, who initially tried different glasses but could not improve things. Clinical examination is unremarkable. How...
Management of giant retinal tears with vitrectomy and perfluorocarbon liquid postoperatively as a short-term tamponade
1 April 2018
| Saruban Pasu
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EYE - Vitreo-Retinal
The authors report an eight year retrospective case series study of 30 eyes of 29 patients with who underwent a giant retinal tear-related retinal detachment repair. M: F ratio was 23:6. Right to left eye ratio was 16:14. The mean...
Retinoblastoma – the challenges of a rare cancer and the role of international partnerships
4 October 2023
| Richard Bowman, Mattan Arazi, Aniruddh Heroor, Kahaki Kimani, M Ashwin Reddy, Ido Didi Fabian, Swathi Kaliki
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EYE - Paediatrics, EYE - Strabismus
Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...
