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In this study, the authors evaluate the efficacy of botulinum toxin A (BTA) as a treatment option for consecutive exotropia. This was a retrospective review of 34 patients; 23 female and 11 male. Age at BTA was a mean of 169 ±88.9 months and follow-up was for a range of 6–84 months (mean 19.8 ±20 months). Eight patients had infantile esotropia and 26 had acquired esotropia; 7 anisometropia, 20 amblyopic, 9 with fusion and 25 with no binocular vision. Pre-treatment angle was 20.03 ±8,42PD for near and 21.41 ±8.87PD for distance. Patients had, on average, 1.6 ±1.1 BTA injections. At 6 months post treatment, angle was 9.65 ±7.42PD for near and 10.82 ±7.33PD for distance. The near angle at 1 month was significantly associated with the 6-month and overall treatment success. Distance angle at 1 month was only moderately associated with the 6-month follow-up, and weak for overall. Presence of fusion had a weak association with 6-month and overall follow-up. Overall success was 73.5%. The authors conclude BTA is an effective alternative treatment option vs surgery for small angle consecutive esotropia.

Botulinum toxin A for management of consecutive exotropia: factors affecting treatment success.
Tugcu B, Yildirim H, Kunduraci MS, et al. 
JOURNAL OF PEDIATRIC OPHTHALMOLOGY AND STRABISMUS
2025;62(4):258–64.
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Fiona Rowe (Prof)

Institute of Population Health, University of Liverpool, UK.

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