Idebenone for Leber hereditary optic neuropathy

The authors present a meta-analysis of studies reporting the effects of idebenone treatment on visual acuity (VA) in patients with Leber hereditary optic neuropathy (LHON), the most common inherited mitochondrial disorder. They included randomised controlled trials, non-randomised controlled trials and...

Systematic review investigating the time taken for corneal stabilisation following contact lens cessation

A systematic literature review of 15 studies (13 prospective, 1 retrospective and 1 case observational case series) to assess corneal stabilisation post-contact lens (CL) cessation by using corneal imaging techniques. The included studies reported stabilisation of corneal parameters as follows;...

Perspectives on sustainability in ophthalmology

This was a prospective study of a multi-item survey aimed to assess and analyse patients’ perception of sustainability and the role of healthcare in general, and ophthalmology in particular. Levels of agreement were measured using a Likert scale. 105 patients...

Long-term comparative outcomes of Hydrus versus iStent inject microinvasive glaucoma surgery implants combined with cataract surgery

This was a retrospective study of 429 eyes (98 phaco-Hydrus (HD), 331 phaco-iStent (IS)) in the overall cohort and 177 eyes (59 phaco-HD, 118 phaco-IS) in the matched cohort over a 48-month period. There was no significant difference in surgical...

Incidence of high IOP following corneal collagen cross-linking

This retrospective cohort study examined 405 patients (405 index eyes and 218 untreated fellow eyes) who underwent cross-linking over a 12-year follow-up duration at Duke Eye Center. Preoperative and postoperative intraocular pressure (IOP) measurements were collected at ~1 month, 3...

Risk factors for ocular complications following orbital fractures

In this Japanese retrospective cohort study, the authors examined records of 416 consecutive orbital fracture patients treated over a 10-year period at a single institution. The study identified ocular complications occurring in 9.5% of the cases, with traumatic mydriasis, hyphaemia...

Identification of potential social determinants which may impact on idiopathic intracranial hypertension

The authors analysed cross-sectional data with the aim of exploring the social determinants of idiopathic intracranial hypertension (IIH). The data was obtained from the National Institute of Health (NIH) All of Us research programme (version 6 – May 2018 to...

Consultations for ‘papilledema’ for inpatients and in the emergency department

This study aimed to establish the final diagnosis and outcomes for neuro-ophthalmology emergency department (ED) and inpatient consultations for ‘papilledema’. Neuro-ophthalmology consults from ED and inpatient wards for adults referred with ‘papilledema’ were prospectively collected for 12-months in a single...

Motor vehicle accident-related eye trauma trends in the United States

The authors present a large retrospective epidemiological study analysing motor vehicle accident-associated eye injuries presenting to US emergency departments between 2000 and 2020. Using a national injury surveillance database (NEISS-AIP), they examined incidence trends, patient demographics and injury patterns over...

Systematic review of BTA vs surgery for partially accommodative esotropia

The authors conducted a systematic review and meta-analysis to evaluate the efficacy of botulinum toxin A (BTA) vs bilateral medial rectus muscle recessions for management of partially accommodative esotropia. They included 4 eligible studies with a total of 521 patients....

Factors associated with surgical success for nasolacrimal duct obstruction

This study reports outcomes and demographic characteristics of children who underwent probing with or without intubation for congenital nasolacrimal duct obstruction (CNLDO) to investigate factors associated with surgical success. This was a retrospective single-centre review of 588 patients; 306 female...

Infantile exotropia surgical outcomes

This study investigates the success rate and dose response of bilateral lateral rectus muscle recessions (BLL) and bilateral lateral rectus muscle recessions plus unilateral medial rectus resection (LMR) on basic type infantile exotropia of 20–45PD. This was a retrospective review...