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A pituitary tumour from 1927
The author shares a clinical case from Edinburgh Royal Infirmary’s archives. It is not often in the course of a clinical career that one gets the opportunity to review a patient who had been treated by a pioneer neurosurgeon some...Photophobia: an unusual symptom of a pituitary macroadenoma
Introduction Photophobia, defined as ‘an abnormal intolerance to light’, is commonly associated with a range of both ocular and neurological pathologies such as dry eye, blepharospasm, corneal pathologies, cataracts, uveitis, retinal dystrophies, optic neuritis, migraine, meningitis, and traumatic brain injury...
Selection of visual field test for detection of pituitary disease
This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...Pituitary adenoma causing compression of the optic chiasm
A 21-year-old girl presented to her general practitioner (GP) with a three-month history of headaches, becoming more frequent and associated intermittent vomiting that did not improve with simple analgesics. There was a strong family history of migraines. She was initially...Pituitary tumours: why are they so often missed?
Part 3: Clinical features, assessment and management (see also Part 2, and Part 1) As previously mentioned in this treatise [1] pituitary tumours are common, occur in all age groups and can present with anything from minimal visual symptoms to...Pituitary tumours: why are they so often missed?
Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...Pituitary tumours: why are they so often missed?
Part 1: Introduction, historical background and Edinburgh connections (see also Part 2 and Part 3) Is there any ophthalmologist who has not missed a pituitary tumour? Hopefully this article will help those currently in practice to avoid such an embarrassment,...
Early diagnosis of pituitary apoplexy using combined MRI findings
The author presents a literature review searching the terms ‘pituitary ring sign’ and ‘sphenoid sinus mucosal thickening’ in the context of pituitary apoplexy from 1990 until the present day. These two findings are both magnetic resonance imaging (MRI) signs of...
OCTA optic disc measurement differences between glaucoma and pituitary macroadenoma
This prospective case-control study aimed to assess the potential of optical coherence tomography (OCT) and OCT angiography (OCTA) in distinguishing between glaucoma and pituitary macroadenoma based on optic disc appearance. Thirty-one patients (23 with glaucoma, eight with pituitary macroadenoma) were...
