This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with a screening protocol for SKP on Octopus perimetry, with Humphrey 24-2 data being extracted from 30-2 results. Of the 50 patients recruited, the 30-2 programme detected visual field loss in 85%, the 24-2 programme in 80% and the Octopus combined kinetic / static strategy in 100% of eyes. Results show that Octopus semi-automated kinetic perimetry is superior to central static testing for detection of pituitary disease related visual field loss. In addition, study findings showed that when conducting kinetic perimetry, the combined use of peripheral (14e) and central (12e) targets increased sensitivity to detection of visual field loss. This study has important implications for test selection in patients with pituitary disease, finding that kinetic perimetry is preferable to central programmes for increased detection of peripheral visual field loss.

Detection of visual field loss in pituitary disease: peripheral kinetic versus central static.
Rowe FJ, Cheyne CP, Garcia-Finana M, et al.
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Claire Howard

Salford Royal NHS Foundation Trust, Salford, UK.

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