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Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

25 years of OCT

David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference

Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...

The past and the future for paediatric ophthalmology

The past 25 years have seen remarkable advances in clinical eye care for children in the UK. This has led to both improved outcomes and better patient and family experiences. There have been substantial changes to patient pathways, major advances...

On becoming a man

It was at the height of the gender debate, with Donald Trump banning transsexuals from serving in the US army and parts of the first world indulging in controversies on whether separate transgender toilets are needed, that a 40-year-old lady,...

RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...

William’s syndrome

William’s syndrome is a congenital multisystem disorder involving the cardiovascular, connective tissue and central nervous systems. The aim of this study was to evaluate the frequency and severity of ophthalmic manifestations and associated diseases as well as provide epidemiology data...

Systemic sarcoidosis presenting with acute myopia and angle closure

Case report A 40-year-old Asian man presented to the Emergency Department with a one day history of sudden onset visual disturbance in his right eye. He complained of image distortion and noted that objects now appeared smaller. He also described...

Q&A: Mr Goel and Mr Loomba on alcohol delamination and phototherapeutic keratectomy (PTK) for the treatment of recurrent corneal erosion syndrome

Recurrent corneal erosion syndrome is a common, recurrent condition caused by abnormal epithelial adhesion to the underlying basal lamina. Spontaneous breakdown of the corneal epithelium can lead to the sudden onset of ocular pain, blurred vision, tearing and photophobia, typically...

Illuminating task lighting

Good lighting is always important but especially for patients who are visually impaired. Janet Pooley provides an overview. We tend to discuss lighting with patients when their vision is reduced, and where we are considering higher reading adds or low...

OCT Angiography in Retinal and Macular Diseases

OCT angiography (OCT-A) is based on the concept that in a static eye, the only moving structure in the fundus of the eye is blood flowing through the vessels. This book explains how the technique allows a depth-resolved analysis and...

Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma

The book is divided into three sections: an introduction to optical coherence tomography (OCT), the OCT in macular diseases, and glaucoma. The first section lists the currently commercially available OCT machines, then describes the techniques for acquiring OCT images using...