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355 results found

Silent keratitis in failed graft

This study examined rates of asymptomatic keratitis in failed full thickness corneal grafts, which were not picked up clinically preoperatively. During a five year period 53 penetrating keratoplasties (PK) were performed for long-standing graft decompensation with stromal opacity and /...

Nanofiber-based hydrogels prevent capsular opacification

Lens refilling is the replacement of the lens with a silicone polymer in an otherwise intact lens capsule. However, capsular opacification (CO), resulting in reduced visual acuity, is a major complication of these injectable accommodating lenses. Opacification is due to...

Anaesthetic drops abuse

A 67-year-old retired female nurse presented with persistent, bilateral, non-healing (>6 weeks) corneal ulcers and stromal ring infiltrates (Figures 1 and 2). The epithelial defects were the result of chemical burns caused by her contact lenses which had been stored...

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device

Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...

Diabetic Macular Oedema

Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...

Understanding amniotic membrane grafts

Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

The embryology of the eye

Nobody claims to like embryology. At least nobody I know. It has been a neglected part of the curriculum since time immemorial and a vicious cycle occurs in which those with an incomplete understanding fail to appreciate the inherent beauty...

RPE tears after intravitreal Lucentis

The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

Jun/Jul 2018 Quiz

History A 35-year-old woman had a long-standing left blind eye following extensive exudative retinal detachment in the past. She later developed increasing pain in her blind eye. Her medical history includes pheochromocytoma resected five years ago, and she is currently...

Feb/Mar 2017 Quiz

History A 40-year-old male patient presented with a right lower eyelid swelling with gradual enlargement for two months. On examination there was a large lesion apparently involving lid margin, part of palpebral conjunctiva and skin. No other local or systemic...