Ripasudil after Descemet stripping in Fuch’s endothelial dystrophy

This study prospectively evaluated the use of ripasudil, a rho kinase inhibitor, in patients undergoing Descemet’s stripping only (DSO) without an endothelial graft for Fuch’s endothelial dystrophy (FED). Patients with dense central guttae limited to the central 5mm of the...

Can intravitreal anti-VEGF injections affect corneal nerves?

This was a retrospective case-control study looking at the effect of anti-VEGF injections on corneal nerves (CN). Fifty-seven patients with a history of at least three anti-VEGF injections in one or both eyes and available confocal microscopic imaging were included...

Does amniotic membrane transplant improve outcomes in chemical injuries?

This single centre, randomised, parallel-controlled clinical trial compared the outcomes of patients with Roper-Hall grade IV ocular chemical injury that had conventional treatment vs. combined medical treatment and amniotic membrane transplantation (AMT). They followed up 60 patients between August 2006...

PUK after corneal crosslinking

This retrospective study aimed to report the incidence, characteristics, clinical presentations, risk factors, and the available treatment modalities of sterile peripheral ulcerative keratitis (PUK) post-corneal collagen crosslinking (CXL). In total 771 eyes of 474 patients operated for keratoconus or ectasia...

How long to air tamponade after DMEK?

This interventional case series looked at the influence of different intraoperative air tamponade times on graft adherence after descemet membrane endothelial keratoplasty (DMEK). A total of 117 eyes with Fuchs endothelial corneal dystrophy (FECD) that underwent DMEK were included. Patients...

Tear production levels and dry eye disease

Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...

Corneal suture sample evaluation

This is a prospective study of 35 patients’ suture samples taken from a tertiary cornea clinic, Miami, Florida, with a history of penetrating keratoplasty. The aim is to study the relationship between corneal suture bacteriology, biofilm and the clinical setting,...

Results of corneal cross-linking in very steep corneas

Corneal cross-linking (CXL) has been shown to be a safe and valid treatment option for progressive keratoconus and have shown an arrest of progression with a low failure rate of 0% to 2.8% in mild to moderate keratoconus. A Kmax...

Corneal cross-linking for treatment of corneal ulcers

This was an observational cohort study looking at the usefulness of photo activated chromophore for infectious keratitis-corneal collagen cross-linking (PACK-CXL) in reducing the time to heal in suppurative corneal ulcers. This study, conducted in a tertiary care centre in South...

Outcomes of corneal cross-linking in paediatric patients compared to fellow untreated eyes

This retrospective cohort study evaluated long-term visual, refractive, topographic and safety outcomes of corneal cross-linking (CXL) in patients younger than 18-years-old with keratoconus. The study included all consecutive paediatric patients who underwent epithelium-off CXL treatment for keratoconus at the study...

Corneal thickness in patients with diabetic peripheral neuropathy

This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...

Microbial keratitis in corneal grafts

The authors report a retrospective case series of 59 episodes of microbial keratitis identified in 41 eyes of 41 patients (39 penetrating keratoplasty (PKPs) and two deep anterior lamellar keratoplasty (DALKs)), from a total of 759 consecutive corneal grafts identified...