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Aug/Sep 2017 Quiz

History A seven-year-old atopic boy has been treated for phlyctenulosis with mild topical steroids. However, he developed dramatic changes at the right limbus in two weeks. He also had past history of vernal keratoconjunctivitis (VKC) with poor compliance to treatment....

Aug/Sep 2015 Quiz 1

History A 60-year-old woman was referred to ophthalmology with a suspected left eye choroidal naevus. Visual acuity was unaffected in both eyes and she was asymptomatic. Ocular history and medical history were unremarkable. Questions Figure 1: Fundus photograph. 1. What...

Ocular toxicity secondary to deferoxamine

Patients with myelodysplastic syndromes can develop transfusion-related iron overload as they become dependent on recurrent blood transfusions [1]. Iron chelation therapy is indicated for the treatment of iron overload and one established example of this is deferoxamine. However, deferoxamine ocular...

A fundal view to warm the heart

In the midst of an overbooked public clinic, wrung dry by medical science, overburdened with the weight of burgeoning patient and organisational demands we feel it is important to occasionally stop and enjoy the small moments – such as this...

New study uncovers key mechanism behind a common genetic cause of age-related visual loss

A groundbreaking study has revealed important insights into the mechanisms behind Fuchs Endothelial Corneal Dystrophy (FECD), a common cause of age-related visual loss, providing hope for future therapeutic developments, and finding implications for other neurological diseases. FECD is a common,...

Large-scale study uncovers demographic and sex factors behind genetic cause of age-related visual loss

A new study has identified a major genetic contributor to Fuchs’ Endothelial Corneal Dystrophy (FECD), a common cause of vision loss, also highlighting the significant roles of sex and ancestry. FECD is a common, inherited eye condition that primarily affects...

Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy

Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy, offering new ways for future therapies to target this common, age-related cause of visual loss. In a landmark study, researchers supported by NIHR Moorfields Biomedical Research Centre, have identified...

Secondary iris-claw anterior chamber lens implantation in patients with aphakia without capsular support

This retrospective, non-randomised, non-comparative, interventional study including 128 eyes of 124 patients that presented with aphakia with no capsular support. All patients consecutively underwent Artisan iris-claw intraocular lense (IOL) implantation between 1997 and 2010. The inclusion criteria were: aphakic without...

Can intravitreal anti-VEGF injections affect corneal nerves?

This was a retrospective case-control study looking at the effect of anti-VEGF injections on corneal nerves (CN). Fifty-seven patients with a history of at least three anti-VEGF injections in one or both eyes and available confocal microscopic imaging were included...

The Worshipful Company of Spectacle Makers awards two Master’s Medals for early career research

The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of two Master’s Medals for 2025. Fabian Yii from Edinburgh was awarded the Master’s Medal for his paper, 'Fundus Refraction Offset as a Personalized Biomarker for 12-Year Risk...

The influence of refraction correction in swept source AS-OCT measurement parameters

Anterior segment (AS) optical coherence tomography (OCT) is the non-invasive technique used to analyse detailed cross-sectional images of the anterior structures of the eye. Swept source (SS) OCT at 1310nm can penetrate deeply into the eye with low levels of...

Apr/May 2019 Quiz

History A 68-year-old female patient was referred from her GP with bilateral conjunctival lesions on her upper eyelids which cause local irritation and dry eyes. Her past ophthalmic history is uneventful. However, systemically she has history of high blood pressure...