Large-scale study uncovers demographic and sex factors behind genetic cause of age-related visual loss
A new study has identified a major genetic contributor to Fuchs’ Endothelial Corneal Dystrophy (FECD), a common cause of vision loss, also highlighting the significant roles of sex and ancestry. FECD is a common, inherited eye condition that primarily affects...
Novel retinal pigment metric tackles bias in AI models
25 February 2025
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AI, oculomics, Moorfields, research, equality, retinal pigment score, RPS, UCL, diversity
Researchers have developed an innovative metric for objectively classifying pigmentation in a retinal image, rather than using subjective social constructs like ethnicity or other demographic variables, as is currently the case when building health datasets. Called the Retinal Pigment Score...
£1 million gift towards world-leading new centre for advancing eye health to enhance education
22 November 2024
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nhs, research, new hospital, London, UK, Schroder Foundation, UCL, Moorfields, developement
The Schroder Foundation and Family have donated £1 million to Moorfields Eye Charity towards the new centre for advancing eye health. The building is under construction and opening in 2027. Oriel is a joint initiative between Moorfields Eye Hospital NHS...
Biomarkers reveal how patients with glaucoma may respond to treatment
Markers in the blood that predict whether glaucoma patients are at higher risk of continued loss of vision following conventional treatment have been identified by researchers at UCL and Moorfields Eye Hospital.
Children with ‘lazy eye’ are at increased risk of serious disease in adulthood
Adults who had amblyopia (‘lazy eye’) in childhood are more likely to experience hypertension, obesity, and metabolic syndrome in adulthood, as well as an increased risk of heart attack, finds a new study led by UCL researchers.
Blindness from some inherited eye diseases may be caused by gut bacteria
Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher.
Transforming eyecare with AI at 100% Optical
4 March 2024
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Pearse Keane, AI, Moorfields, UCL, technology, advancement, artificial intelligence, development
“We are drowning in people we need to see in hospital eye services, and some people are going blind as a result. We are looking at nearly 10m hospital appointments for ophthalmology a year, with an approximately 33% increase over...
£5 million award for world-leading research facilities within new eye health centre
12 February 2024
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research, infrastructure, Sir Jules Thorn, education, trust, moorfields, UCL, NHS, Oriel
The Sir Jules Thorn Charitable Trust has awarded £5 million to UCL in partnership with Moorfields Eye Charity and Moorfields Eye Hospital to support Oriel – a centre for advancing eye health, opening in 2027.
Effective treatment for rare sight-threatening infection
A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.
World-first artificial intelligence foundation model for eye care to supercharge global efforts to prevent blindness
22 September 2023
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oculomics, AI, moorfields, big data, RETFound, ChatGPT, UCL, artificial intelligence
Researchers at Moorfields Eye Hospital and UCL Institute of Ophthalmology (IoO) have developed an artificial intelligence (AI) system that has the potential to not only identify sight-threatening eye diseases but also predict general health, including heart attacks, stroke and Parkinson’s disease.
Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis
22 August 2023
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moorfields, Parkinson's disease, Siegfried Wagner, Pearse Keane, UCL Institute of Ophthalmology, early detection
A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.
