Changes in extraocular muscle after the Faden procedure – animal histopathology model
Reviewed by Fiona Rowe

The authors studied the histological changes in the anterior part of the posterior fixation suture including the myoscleral junction, after the Faden operation in eight rabbits. The Faden operation was undertaken in one eye and the fellow unoperated eye served as a control. Muscles were examined at six weeks follow-up. The Faden eye showed significant differences in fibrosis, acute inflammation, chronic inflammation and foreign body reaction. Diffuse fibrosis was observed at the myoscleral junction and in the anterior part of the muscle to the posterior fixation suture. They propose that reoperation after Faden would be unpredictable and impossible because of very little viable muscle anterior to the stitches. The authors acknowledge this is a small animal study with related limitations.

Histopathologic change in the anterior part of the posterior fixation suture after a Faden operation in an animal model.
Kim S-H, Kang E, Kang B, Ha S-G.
JOURNAL OF PEDIATRIC OPHTHALMOLOGY AND STRABISMUS
2024;61(5):371–5.