Journal Reviews archive for 2018
Progression of high anisometropia in children
This study aimed to analyse the stability and progression of higher degrees of myopic anisometropic in children. This retrospective study included 63 children meeting the inclusion criteria. Mean age at initial visit was 4.3 years ±2. There were 51% males...
Simultaneous surgery for ptosis and strabismus
The authors present the surgical management of congenital ptosis and coexistent strabismus at one centre for a follow-up period of >2 years. This was a retrospective review of 10 patients (17 eyes); nine males. Intermittent exotropia was present in three...
MRI in anisometropic amblyopia
This study recruited patients with anisometropic amblyopia in the right eye and without strabismus. This allowed the authors to reduce the effort exerted in cortex activities by different amblyopic eyes. They used whole brain analysis to find the differences between...
Open-field autorefraction screening
This study aimed to determine the efficacy of the Shin-Nippon NVision-K5001 autorefractometer using the open-field refractometry principle in the elimination of accommodation in children. One hundred and fourteen patients aged three to six years were recruited. After excluding ocular pathology...
Repeated ptosis surgery
The purpose of this study was to evaluate the amounts of surgery for the treatment of residual or recurrent simple congenital ptosis and to investigate the relationship between long-term surgical success rates with clinical and surgical factors. This was a...
Reduction of severe visual loss and complications following IAC for RB
This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...
PRN Ranibizumab verses continuous aflibercept in UK clinical practice
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...
Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)
The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...
Macular atrophy with aflibercept
The authors of this paper set out to investigate the prevalence of macular atrophy in treatment-naive patients with neovascular AMD undergoing aflibercept monotherapy (three monthly loading injections followed by subsequent treatment every two months). Case notes over a three year...
Cataract in patients with pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...
Cataract surgery in patients being treated for neovascular AMD
This retrospective matched case control study evaluated outcomes and predictive factors of visual acuity (VA) change after cataract surgery in patients being treated for neovascular age related macular degeneration (nAMD). They compared 124 patients that had cataract surgery with 372...
Low dose steroids for ocular dry eye disease in graft vs. host disease
This double-masked randomised clinical trial compared the response of dry eye disease (DED) to treatment with topical steroids in patients with and without graft vs. host disease (GVHD). Forty-two patients in a single centre (n=21 with and n=21 without GVHD)...
