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Retinoblastoma – the challenges of a rare cancer and the role of international partnerships

Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...

A diagnostic imaging technique for optic pathway tumours

The authors discuss the difficult clinical scenario of patients with deteriorating visual function and an optic pathway lesion. The morbidity associated with biopsy means a highly sensitive and specific imaging technique would be of great value. The authors describe the...

Results of changed treatment for retinoblastoma

Systemic chemotherapy was adopted in Kobe in 1996. In this study the authors analyse the clinical manifestations and results of treatment for patients with retinoblastoma since then. This review is of 43 eyes of 34 patients. Those with follow-up to...

Prognosticating ocular adnexal lymphoma

The authors retrospectively analyse 160 patients with primary ocular adnexal lymphoma to determine the accuracy of prognosis based on the Ann Arbor classification and how this compares to the accuracy of prognosis based on retrospectively applying the newer Tumor, Node,...

Aug/Sep 2018 Quiz

History A seven-year-old girl presented with a presumed papillomatous lesion on right inferior fornix (Figure 1). Her parents said the lesion was increasing in size for two weeks. CT scans (Figure 2) revealed a lesion occupying the right medial canthus....

Oct/Nov 2017 Quiz

History A 73-year-old man presented with a rapidly growing left lower eyelid lump with recent bleeding. On examination there was a raised, ulcerated, firm mass occupying two thirds of his lower eyelid. The lesion bled easily and appeared connected to...

Dec/Jan 2019 Quiz

History A 72-year-old male presented to his GP with a large ulcerated lesion on his right lower eyelid present for six months and enlarging in size. He had an urgent referral to a tertiary centre for specialised examination. The lesion...

Jun/Jul 2017 Quiz

History A 57-year-old female patient presented with gradual painless diplopia over the last six months. Examination revealed restricted upward eye movements and 4mm proptosis which did not increase with Valsalva manoeuvre. Intraocular pressure was normal, no visual defects were noted,...

Feb/Mar 2017 Quiz

History A 40-year-old male patient presented with a right lower eyelid swelling with gradual enlargement for two months. On examination there was a large lesion apparently involving lid margin, part of palpebral conjunctiva and skin. No other local or systemic...

Videos - iStent Inject

Trabecular bypass surgery with iStent Inject enhances aqueous outflow from the eye , evidence of this is demonstrated through Angiographic visualization of aqueous humor outflow in studies conducted by Dr. Alex Huang M.D, Ph.D

Viral uveitis

This review covers viral causes of anterior uveitis. A viral aetiology should be suspected when anterior uveitis is accompanied by ocular hypertension, diffuse stellate keratic precipitates or the presence of iris atrophy. Most common viruses associated are herpes simplex, varicella-zoster...

Trabeculectomy ab interno (trabectome)

This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...