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100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

A Multidisciplinary Approach to Neovascular Glaucoma in a Patient with Waldenström’s macroglobulinemia

An 84-year-old Caucasian male attended eye casualty with a four month history of reduced vision, a dull ache and photophobia in both eyes. He had also reported dizziness, weakness and intermittent epistaxis in the nine months prior to presentation. There...

SOS (Simplified Ophthalmic Statistics) Part 4: How to present your statistical analysis

This is the last in this series of short guides which we hope provide some guidance in relation to statistical issues researchers may encounter when conducting research, audit or indeed quality improvement projects. Here we focus on an issue that...

Prediction errors of formulas in optical biometers

This study was conducted retrospectively in a private practice setting. Nine formulas were compared for prediction error (postoperative spherical equivalent (SE) minus, predicted SE calculated by each formula), using two optical biometers (Lenstar – optical low coherence reflectometry (OLCR) and...

Lockdown and eye health – a case of accommodative spasm

A 25-year-old male presented to the eye casualty with a one-day history of sudden onset worsening vision. More specifically, he noted his vision was more blurred than usual and this was more exaggerated for near-work than for distance-work. He was...

Strabismus and ocular motility, demystified

I am a former orthoptist, now trained in medicine and working as a foundation doctor. In my previous work, I was frequently approached by ophthalmology trainees eager for guidance with strabismus and ocular motility. Drawing on my clinical experience, I...

In vivo confocal microscopy, principles and use in keratitis Part 1: Principles

In 1968 Maurice introduced the concept of high powered specular microscopy, it was in that very year that the first scanning confocal microscope was proposed. Marvin Minsky developed the first confocal microscope in 1955 named the ‘double focusing scanning microscope’....

The results of the last survey Feb23

*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. For the...

Complex Biometry Clinics: a new service development

In this article we describe a new local service development, the ‘Complex Biometry Clinic’ at Leicester Royal Infirmary. Retrospective data analysis of patients referred between October 2012 and October 2013 was performed. The aim was to provide a one-stop service...

Is lens constant optimisation for IOLMaster indispensable in order to achieve a good refractive outcome?

A study of refractive outcomes following cataract surgery was carried out with the aim of comparing the postoperative refractive outcomes against Royal College of Ophthalmologists standards and to determine the extent of association between accuracy of intraocular lens (IOL) power...

Preventing refractive surprises by real time biometry during cataract surgery

A few months ago a retired lady presented for second eye cataract surgery. I noted on the pre-op ward round that the outcome of her first eye’s surgery looked like a refractive surprise as her spherical equivalent in that eye...

Stem cell transplantation and pterygium surgery

Pterygium is a benign, fibrovascular overgrowth of bulbar conjunctiva extending onto the cornea and has been associated with ultraviolet (UV) light exposure. The prevalence of pterygium worldwide varies between geographical zones but has been reported to range between three and...