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Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service
Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...Advances and developments in medical retina
The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...Technology in ophthalmology – a promising future and what we need to know about the regulations
Undoubtedly, ophthalmology is one of the greatest sources of inspiration for technological progress in medicine. Thus far, we have seen remarkable advancements in the technology used by ophthalmologists across all subspecialties. From simplifying common procedures, to treating previously incurable conditions,...Vitreomacular traction and full thickness macular hole
Clinical scenario: A 64-year-old lady presented to the clinic with a few weeks history of sudden onset of metamorphopsia, central blur and reduced vision in her right eye. The ocular examination and ocular coherence tomography confirmed right eye focal vitreomacular...Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)
Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...AOP fee reduction for members amidst coronavirus crisis
The Association of Optometrists (AOP) has announced a 20% reduction in membership fees for UK practising members, which is the equivalent of two monthly direct debit payments.Review evaluates efficacy of eye protection equipment to protect against Covid-19
Researchers from the University of Oxford have concluded that there is "no direct evidence from randomised trials that eye protection equipment alone prevents transmission of COVID-19."BCPB chair takes on Everest challenge
BCPB's Chair, Paul Hunter is climbing Mount Everest at home via his stairs during lock down to raise vital funds for the charity's blindness prevention work.Meet Robyn our News & Events Co-ordinator
ROBYN COOPER, News & Events Co-ordinator. Robyn joined Pinpoint Scotland a few months ago and would be delighted to hear from you. If you have a course or conference...Retina UK Professionals' Conference 2023
The Retina UK Professionals’ Conference will be held in-person and online on Friday 8 July 2022 and will look at what our community has told us they need in terms of support from the charity and health sectors. You will...
