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Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....

Three years of experience with quantiferon-TB Gold Testing in patients with uveitis

Quantiferon-TB Gold is a new alternative to the tuberculin skin test that utilises synthetic peptides representing M. tuberculosis antigens ESAT-6, CFP-10, TB7.7 and upon incubation with whole blood IFN-γ is released from pre-sensitised T cells and can be measured by...

New Treatments in Noninfectious Uveitis

As a specialist registrar training in Aberdeen there were two important lessons I learned which have proved to be invaluable over the years for two very different reasons. The first lesson learned was to never underestimate the wind chill factor...

Eyes on the road – visual standards for car drivers

The author examines the current visual standards required by drivers and asks whether more needs to be done to make roads safer. Are the public adequately protected by the current system of visual standards required by drivers? In a survey...

Zeiss Forum

The tech column this issue reports on the features and experience of using the Zeiss Forum software. I have overseen the installation, troubleshooting, training and use of the software over the last two years. As both a consultant specialising in...

Does paediatric uveitis reactivate after treatment with anti-TNF-a drugs?

As a potentially blinding disease that can affect 7-27/100000 children, uveitis remains a rare condition, where little evidence based data is available to guide management decisions. Most paediatric uveitis cases are chronic, anterior and non-infectious and may be associated with...

A career in uveitis

As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...

Safety and outcome of microincision vitreous surgery in uveitis

This paper reports the outcomes of microincision vitreous surgery (MIVS) 23G/25G in uveitis of 103 patients (106 eyes) who underwent diagnostic MIVS over a period of four years at the Advanced Eye centre in Chandigarth India. The postoperative evaluation included...

Methotrexate and mycophenolate mofetil for non-infectious uveitis

This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...

Medical malpractice in uveitis: a review of clinical entities and outcomes

This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....

Is pre-eclampsia / eclampsia a risk factor for non-infective uveitis?

This population based retrospective matched cohort study was the first of its kind to suggest an association between preeclampsia / eclampsia (PEE) and non-infective uveitis (NIU). They used the Longitudinal National Health Insurance database in Taiwan to assess 2073 post-delivery...

Persistent anterior uveitis after cataract surgery

This retrospective cohort study was completed to help identify potential risk factors for developing persistent anterior uveitis (PAU) following uncomplicated cataract surgery in patients with no prior history of uveitis or autoimmune disease. A total of 3013 eyes (2019 patients)...