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273 results found

IOP in children with uveitis

This is a retrospective study of paediatric uveitis (<16-years-old) between July 2002 to June 2016 of a total of 320 children from a single centre: 17.2 % (55/320 patients) developed raised IOP requiring therapy; 11.5% of eyes required glaucoma surgery...

Cataract surgery in uveitis

This is a multicentre study of eight UK independent sites of patients with uveitis, undergoing cataract surgery between January 2010 and December 2014. A total of 1173 eyes were compared with a control reference group of 95,573 eyes from the...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

In conversation with Dr Robert B Nussenblatt

Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...

The science of glaucoma management: highlights of the 2020 Moorfields International Glaucoma Symposium

Held earlier this year, the 12th annual Moorfields International Glaucoma Symposium provided a forum for advanced clinical and scientific exchange in glaucoma management. The authors describe the key presentation themes and debates, highlighting specific topics of interest to glaucoma specialists....

Zeiss Forum

The tech column this issue reports on the features and experience of using the Zeiss Forum software. I have overseen the installation, troubleshooting, training and use of the software over the last two years. As both a consultant specialising in...

Three years of experience with quantiferon-TB Gold Testing in patients with uveitis

Quantiferon-TB Gold is a new alternative to the tuberculin skin test that utilises synthetic peptides representing M. tuberculosis antigens ESAT-6, CFP-10, TB7.7 and upon incubation with whole blood IFN-γ is released from pre-sensitised T cells and can be measured by...

Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....

Eyes on the road – visual standards for car drivers

The author examines the current visual standards required by drivers and asks whether more needs to be done to make roads safer. Are the public adequately protected by the current system of visual standards required by drivers? In a survey...

New Treatments in Noninfectious Uveitis

As a specialist registrar training in Aberdeen there were two important lessons I learned which have proved to be invaluable over the years for two very different reasons. The first lesson learned was to never underestimate the wind chill factor...

Does paediatric uveitis reactivate after treatment with anti-TNF-a drugs?

As a potentially blinding disease that can affect 7-27/100000 children, uveitis remains a rare condition, where little evidence based data is available to guide management decisions. Most paediatric uveitis cases are chronic, anterior and non-infectious and may be associated with...

A career in uveitis

As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...