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Management of a giant pigment epithelium detachment with transition from half- to full-dose aflibercept

This case report describes the management of a giant pigment epithelial detachment (PED) in neovascular age-related macular degeneration (nAMD) using half-dose aflibercept. An 80-year-old woman presented with a huge PED (maximum height 1338µm) and multiple risk factors for retinal pigment...

Management of large hypertropia due to lost inferior rectus

This case report outlines the management strategy for a 37-year-old male who suffered a penetrating left orbital injury with rupture of the inferior rectus muscle, optic nerve avulsion and vertical deviation of about 90PD. On orbit exploration, the inferior rectus...

Low-dose bimatoprost/timolol gel: a new fixed-combination option

This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...

Optical coherence tomography in patients exposed to vigabatrin

Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...

Act now: Professor Serge Resnikoff on making myopia a public health priority

Over the past decade, myopia has shifted from a common childhood inconvenience to what global health leaders now call a “public health emergency in slow motion” [1]. According to Professor Serge Resnikoff, former Head of Eye Health at the World...

Neurofibromatosis type 2 – diagnosis, features and MDT approach

NF2 is a genetic condition caused by mutation in a single gene (NF2 gene) on chromosome 22. The NF2 gene provides instructions to produce a protein called merlin, also known as schwannomin. This protein functions as a tumour suppressor, preventing...

Is intracranial pressure affected by the valsalva manoeuvres and exercise?

Idiopathic intracranial hypertension (IIH) is characterised by elevated intracranial pressure (ICP), which leads to optic nerve head swelling and a risk of visual loss. The impact of straining and exercise on ICP regulation is poorly understood yet clinically relevant to...

Long-term results of cross-linking treatment for keratoconus

The authors report on the long-term outcomes in a prospective case series of patients with keratoconus undergoing corneal collagen cross-linking (CXL) treatment. Thirty-two patients (40 eyes; mean age 22.5+/-5.5 years) with Grade I, II and III progressive keratoconus were recruited...

Apply now for subspecialty fellowships in Singapore

The Singapore National Eye Centre is inviting applications for the following clinical fellowships

OSA signs further 10 year deal with 100% Optical

The OSA and Media 10, owners of 100% Optical, have signed a further ten-year agreement to work together. This follows the three-year agreement which has been in place since the closure of Optrafair. The securing of this long-term relationship between...

Attitudes to strabismus in an Ethiopian population

The authors conducted a community-based cross-sectional study in Gondar town (NW Ethiopia) in April 2019 of all eligible adults with a two-stage random sampling procedure for recruitment. Six hundred and two participants were included with a response rate of 94.9%...

Ocular bubbly: a vitreoretinal update on the art of gases

The authors remind us of the revolutionary impact gases have had on retinal surgery. In 1938, Rosengren attempted to improve his retina repair surgical outcomes [1]. He discovered that suturing the retina or pressing externally on the sclera were not...