You searched for "Gene"
Blindness from some inherited eye diseases may be caused by gut bacteria
Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher.
Myopia-protective against diabetic retinopathy
1 October 2016
| Bheemanagouda Patil
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EYE - Vitreo-Retinal
This meta-analysis evaluates the current evidence of the relationship between myopia and diabetic retinopathy (DR) risk. A systematic search was performed up to April 2015. Three models were used to assess the association between myopia and risk of DR: axial...
Retinoblastoma management update (part 1): clinical features, diagnosis and genetics
1 January 2017
| Manoj V Parulekar
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EYE - Oncology
The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...
Lamellar patch grafts utilising cornea remnants from DMEK/PKP
The authors retrospectively reviewed 23 lamellar patch grafts performed over a six-year period for tectonic indications in corneal thinning and perforations. The anterior stroma of corneal endothelium peeled for descemet membrane endothelial keratoplasty (DMEK) were used to prepare circular lamellar...How to win presentation medals
1 August 2014
| Gwyn Samuel Williams
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EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Having been to many tens of thousands of ophthalmology registrar presentation competitions and seen the types of presentations that consistently impress the judges, as well as the ones that fail to make the grade, I feel it is my humble...
Large-scale study uncovers demographic and sex factors behind genetic cause of age-related visual loss
A new study has identified a major genetic contributor to Fuchs’ Endothelial Corneal Dystrophy (FECD), a common cause of vision loss, also highlighting the significant roles of sex and ancestry. FECD is a common, inherited eye condition that primarily affects...Worshipful Company of Spectacle Makers awards silver medal to Professor Robert Maclaren
At a Court Lunch held in the historic Apothecaries’ Hall last week, the Worshipful Company of Spectacle Makers awarded its prestigious Silver (Fincham) Medal to Professor Robert MacLaren. Professor MacLaren is Professor of Ophthalmology at the University of Oxford, Consultant...Genetic profiling for personalised healthcare solutions in AMD – an update
1 August 2015
| Rod McNeil
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...
In conversation with Robert Henderson
Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...3rd Ophthalmic Drug Delivery Summit
28 January 2025
-30 January 2025
Translating Long Lasting Efficacy & Less Invasive Retinal Drug Delivery The importance of matching the right drug delivery route to the right ophthalmic disease is more pressing than ever. The 3rd Ophthalmic Drug Delivery Summit is the premier gathering for...
Leber’s hereditary optic neuropathy: from lab to clinic
1 October 2016
| Chrysostomos D Dimitriou
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EYE - Neuro-ophthalmology
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Hereditary optic neuropathy, Leber hereditary optic neuropathy, mitochondrial optic neuropathy, optic neuropathy
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
Age-related macular degeneration
1 December 2015
| Nana Theodorou
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EYE - Vitreo-Retinal
This review article offers an up to date review of the genetic and environmental risk factors associated with aetiology surrounding age-related macular degeneration (AMD). The article briefly describes the typical clinical presentation relating to early and late stages of the...
