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Ranibizumab safety in pregnancy

Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...

Evaluation of Optive® in ocular discomfort after anti-VEGF intravitreal injection

In this study the authors prospectively evaluated the efficacy of Optive® eye drops after in full, then abbreviation - intravitreal injection (IVT). Patients naïve to IVT were included in the study. No artificial tear treatment was prescribed after the first...

Comparison of the efficacy of anti-VEGFs agents in nvAMD

This retrospective multicentric study conducted in Israel and Canada, compared the efficacy of bevacizumab, aflibercept 2mg and ranibizumab as first-line treatments for neovascular age-related macular degeneration (nvAMD). Included were treatment-naïve nvAMD eyes receiving ≥12 months of treat-and-extend (T&E) anti-VEGF therapy...

Safety and outcome of microincision vitreous surgery in uveitis

This paper reports the outcomes of microincision vitreous surgery (MIVS) 23G/25G in uveitis of 103 patients (106 eyes) who underwent diagnostic MIVS over a period of four years at the Advanced Eye centre in Chandigarth India. The postoperative evaluation included...

Full thickness macular hole after YAG PI

The authors report a case of macular hole post YAG peripheral iridotomy (PI) of a patient with pre-existing vitreomacular adhesion. Although a relatively safe procedure, some anterior segment complications are well documented such as corneal endothelium damage, rise in IOP,...

Cystoid macular oedema following cataract surgery

This review covers the history, incidence, diagnosis, risk factors, pathophysiology and medical management of postoperative macular oedema (PCMO), with a particular emphasis on key contemporary studies and novel observations. The authors revisit the incidence of well-established risk factors including intraoperative...

IOL tilt with air tamponade vs. salt solution

In this study the authors made a comparison of significant postoperative tilt of IOL with air tamponade as opposed to balanced salt solution, in the procedure of combined phaco with IOL and vitrectomy. Thirty-four patients were included into the analysis....

Caffeine concentration in the vitreous after drinking coffee

Caffeine is known to penetrate many bodily fluids, including the vitreous. In this prospective study, investigators measured caffeine levels in vitreous samples from patients undergoing vitrectomy and epiretinal membrane peel. Patients were divided into habitual and non-habitual coffee drinkers. One...

Retinal traction during ERM peeling

This prospective study aimed to quantify the retinal thickening induced by epiretinal membrane (ERM) peeling and to correlate this thickening with postoperative retinal function. Twenty-five patients who required surgery for idiopathic ERM were included in the study. The authors performed...

Associations between cerebral vascular malformations and retinal venous malformations

The authors present a retrospective medical notes review which aimed to understand associations between retinal venous malformations (RVM) and cerebral vascular malformations (CVM). Cases of known CVM over a four-year period were identified. The data extracted from medical records included...