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Suspected vitreous seeding of uveal melanoma

1 December 2016 | | EYE - Pathology, EYE - Oncology | Choroid, Neoplasia, Vitreous
This is a retrospective non-randomised study of 23 patients with consecutive uveal melanoma who underwent diagnostic vitrectomy between the period of January 2000 and November 2013. The reason for vitrectomy was suspected dissemination of tumour cells inside the eye. The...

The results of the last survey Jun24

3 June 2024 | | EYE - Cataract, EYE - Refractive
When I was in my training and even in my early years as a consultant, I did not fully understand the difference between different lenses. When asked my preference of hydrophilic versus hydrophobic intraocular lenses (IOLs) I really did not...

An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

5 April 2022 | | EYE - Cornea, EYE - General
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

Ophthalmology history and examination – a guide for medical students

15 February 2023 | | EYE - General
*First author Students have very little exposure to ophthalmology during their years at medical school. Teaching consists of a handful of lectures followed by a short placement in which students are expected to practise histories and examinations on patients with...

Sexually transmitted conjunctivitis – the REALLY sticky eye

5 October 2020 | | EYE - Cornea, EYE - General
Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...

Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

1 October 2018 | | EYE - General
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

The science of glaucoma management: highlights of the 2020 Moorfields International Glaucoma Symposium

5 October 2020 | | EYE - Glaucoma, EYE - General
Held earlier this year, the 12th annual Moorfields International Glaucoma Symposium provided a forum for advanced clinical and scientific exchange in glaucoma management. The authors describe the key presentation themes and debates, highlighting specific topics of interest to glaucoma specialists....

Advances in the understanding, diagnostic and treatment of keratoconus

1 December 2022 | | EYE - General
*Joint first authors Keratoconus is a bilateral and asymmetric eye condition in which the cornea’s structure is affected and thinned, causing a cone-shaped bulge to develop. This results in progressive loss of vision and impairs the ability of the eye...

Intraocular lens choice in patients who have undergone previous corneal refractive surgery

3 June 2026 | | EYE - Cataract, EYE - Cornea, EYE - Refractive
Patients who underwent vision correction in their 20s to 40s are now entering their 50s and 60s, the typical starting age for cataract development [1]. Consequently, ophthalmologists are increasingly encountering patients whose corneal profiles have been surgically altered, requiring advanced...

Corneal transplantation in the United Kingdom: are we blind to the challenges that still exist after the Organ Donation Bill?

28 November 2022 | | EYE - Cornea, EYE - General
Corneal transplantation (CT) is a significant treatment option for a huge number of patients in the United Kingdom (UK) [1]. For an individual, CT results in a substantial improvement in quality of life. Penetrating keratoplasty with full thickness grafting has...

Your 101 guide to interpreting the Pentacam®

3 June 2026 | | EYE - Imaging, EYE - Cornea
Anterior segment tomography produces a three-dimensional assessment of anterior and posterior corneal structures. The Pentacam uses rotating Scheimpflug imaging to generate cross-sectional scans of the cornea and anterior chamber, essential for detecting ectasia, refractive surgery screening and longitudinal monitoring. However,...

Crystalline keratopathy in monoclonal gammopathy of undetermined significance

2 April 2025 | | EYE - Cornea
Monoclonal gammopathies encompass a group of plasma cell disorders characterised by the excessive production of abnormal monoclonal immunoglobulins in the bloodstream [1]. This category includes multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), amyloidosis and other lymphoproliferative disorders. Monoclonal gammopathy...