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Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

4 December 2023 | | EYE - Neuro-ophthalmology
An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...

Embryology in clinical practice

1 February 2016 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...

Cortical blindness

1 August 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Cortical blindness is a rare but recognised entity. Cerebrovascular accident is a well-known risk factor. We report a case of an 84-year-old lady with bilateral cortical blindness with multiple cardiovascular risk factors. Case report An 84-year-old lady was admitted under...

Neurofibromatosis type 2 – diagnosis, features and MDT approach

1 December 2021 | | EYE - Orbit, EYE - Vitreo-Retinal, EYE - Cataract, EYE - Refractive, EYE - General
NF2 is a genetic condition caused by mutation in a single gene (NF2 gene) on chromosome 22. The NF2 gene provides instructions to produce a protein called merlin, also known as schwannomin. This protein functions as a tumour suppressor, preventing...

Strengthening the signal: Advancing oculomics research for systemic health insights

4 December 2024 | | EYE - Imaging
Oculomics, the study of how ocular structure reflects systemic health, is poised to become an integral tool for predicting, triaging, and diagnosing a wide range of diseases. By analysing data from the eye, particularly the retina, healthcare providers can gain...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

1 February 2017 | | EYE - Oncology
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

Herpes zoster ophthalmicus: the essentials

24 July 2020 | | EYE - Cornea, EYE - General
Herpes zoster, also referred to as shingles, is a common infection most typically caused by the reactivation of varicella zoster virus that lies dormant (sometime for decades) in the dorsal root nerve ganglion following primary chickenpox infection [1]. In 10-20%...

What not to miss in neuro-ophthalmology Part 1

1 April 2018 | EYE - Neuro-ophthalmology
Neuro-ophthalmology is a complex and difficult subspecialty in ophthalmology. It has several connections to neurology, neuro-surgery, rheumatology as well as many other medical specialties. Working in an multidisciplinary team (MDT) environment is key to success in this subspecialty as mistakes...

End stage glaucoma management

1 August 2014 | | EYE - Glaucoma
A 48-year-old female has had multiple drug treatment for glaucoma and is still losing field of vision. How do you manage this over time? This patient is at high-risk for going blind and should be managed aggressively to protect remaining...

Optic nerve swelling – your survival guide (part 2)

1 December 2017 | | EYE - Neuro-ophthalmology
In this second article we will discuss bilateral optic nerve swelling, its aetiology, various investigations and possible treatments. We will also discuss various protocols used in the management of suspected optic nerve swelling cases. (Part one of this topic available...

Sight Scotland partners with Pleasance to boost accessibility for thousands at Edinburgh Fringe

12 August 2025 | the culture section, Scotland, patient stories, charity
Sight Scotland, supported by Sight Loss Councils, has partnered with famous fringe venue the Pleasance to deliver specialist visual impairment awareness training to over 250 of its staff ahead of this year’s Edinburgh Festival Fringe. The training is set to...

Educational concerns and anxiety levels amongst ophthalmology trainees during the COVID-19 pandemic

5 June 2020 | | EYE - General
How concerned are ophthalmology trainees about the present impact and the future consequences of suspended ophthalmic training programmes? Researchers in the West of Scotland investigate. Anxiety, stress and the longer-term stress reaction of burnout often go unrecognised, yet are known...