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Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | EYE - Vitreo-Retinal, EYE - General
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Treatment of diabetic macular oedema

1 June 2014 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...

Inherited retinal disorders now the leading cause of blindness

1 April 2014 | | EYE - Vitreo-Retinal
The recent paper in BMJ Open, from the UCL Institute of Ophthalmology, ‘A comparison of the causes of blindness certifications in England and Wales in working age adults (16-64 years), 1999-2000 with 2009-2010’ concludes that inherited retinal disorders (IRD) such...

Innovations in posterior uveitis: In conversation with Dr Colin Chu

1 July 2025 | | EYE - Imaging
A research team has been awarded significant funding by the National Institute for Health and Care Research (NIHR) to develop an innovative drug-device combination that aims to revolutionise how individual immune cells are monitored and treated in patients at Moorfields...

Cancer associated retinopathy

7 December 2020 | | EYE - Vitreo-Retinal, EYE - General
Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...

AI breakthrough in detecting leading cause of childhood blindness

3 May 2023 | AI, blindness, Children
An artificial intelligence (AI) tool could be an effective way of identifying retinopathy of prematurity (ROP), the leading cause of childhood blindness in middle-income countries, finds a new study led by UCL and Moorfields Eye Hospital researchers.

SCONe Project seeks participants for patient and public involvement group to revolutionise AMD research

29 April 2024 | baljean dhillon, SCONe, project, research, scotland, edinburgh, AMD, call to action
The SCONe project, run by optometrists, ophthalmologists, and researchers from the University of Edinburgh, and funded by Sight Scotland, is appealing for participants to take part in a Patient and Public Involvement (PPI) group focused on revolutionising the detection and management of Age-Related Macular Degeneration (AMD).

AI predicts eye damage from autoimmune drug, years before symptoms appear

1 September 2025 | artificial intelligence, hydroxychloroquine, pharmacology, research, Moorfields
A novel AI tool could transform screening for patients taking hydroxychloroquine by spotting early signs of eye damage, according to a study published in Opthalmology Retina. Researchers have devised an artificial intelligence (AI) system that can detect and predict serious...

The pyramid

1 December 2017 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
The first time I attended the Congress of the Royal College of Ophthalmologists was now more than 10 years ago, though I still remember the excitement of wandering down the aisles in the exhibition hall marvelling at the stands and...

The Leicester Grading System for Foveal Hypoplasia

1 April 2020 | | EYE - Paediatrics, EYE - Neuro-ophthalmology, EYE - Orbit, EYE - General
The University of Leicester Ulverscroft Eye Unit have published the first medical grading system named after the city of Leicester. Infantile nystagmus is characterised by constant and involuntary eye movements and affects 24 per 10,000 people [1]. Onset is usually...

Acute management of retrobulbar haemorrhage

1 February 2022 | | EYE - Orbit, EYE - Oculoplastic
The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Flashes and floaters in community optometry – diagnosing a posterior vitreous detachment

1 October 2018 | | EYE - General
Managing patients who attend a practice with symptoms of flashes and floaters is a regular occurrence in community optometric practice. It’s often very distressing for patients; symptoms can be quite dramatic and an internet search can indicate imminent blindness from...