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753 results found

Trial of low-concentration bimatoprost and timolol eye gel versus higher concentrations

This is an international, multicentre, randomised, parallel group, investigator-masked study of 554 patients, having insufficient control of intraocular pressure (IOP) with a first-line monotherapy and requiring dual therapy. Two hundred and eighty patients were randomised to receive low concentration (BTFCEG...

Step-by-step guide to mastering skills with the Goldmann applanation tonometer

Ophthalmology is a highly specialised field that requires proficiency in various diagnostic skills for numerous conditions. Entrants into ophthalmology at ST1 often possess minimal to no ophthalmic experience beyond what they learned in medical school. Consequently, they may face significant...

Influence of hormone treatment on choroidal development in isolated growth hormone deficiency patients

This study evaluated retinal parameters and choroidal structure in children with isolated growth hormone deficiency (IGHD) to compare them with healthy children and to find out if these parameters are affected by recombinant human growth hormone treatment. This was an...

Understanding the extracellular matrix in uveal melanoma

This review examines how the extracellular matrix (ECM) is remodelled throughout uveal melanoma development, from the eye to the liver. Uveal melanoma, the most common primary intraocular malignancy in adults, carries a poor prognosis due to its propensity for hepatic...

Accuracy of AI chatbots in providing reliable paediatric ophthalmology responses

The authors aimed to explore the strengths and weaknesses of 2 different large language model (LLM) chatbots (ChatGPT4.0 and DeepSeek-RI) in providing reliable and access information about paediatric ophthalmology. The study used 44 multiple choice questions covering topics from the...

Serendipity

“Serendipity is looking in a haystack for a needle and discovering a farmer’s daughter” – Julius Comroe Jr (Surgeon, Medical Researcher and Author) One of the attractive features of ophthalmology, apart from the good quality of life and the relatively...

Feb/Mar 2015 Quiz 1

A 79-year-old male presented to the ophthalmic emergency department with a three week history of left eye pain. He also reported visual deterioration in the left eye over the same period. He suffered from degenerative myopia, with his spectacle prescription...

Case series of toxic anterior segment syndrome

Herein we report two cases of toxic anterior segment syndrome (TASS) following uneventful cataract surgery. Both patients presented 24 hours after their uneventful operations with painless blurred vision in the operated eye. The inflammatory reaction was controlled successfully with an...

Grading of ocular inflammation in uveitis: an overview

Anterior uveitis is the commonest form of uveitis, which can lead to severe morbidity if not treated appropriately [1]. Data from general ophthalmology practices suggest around 90% of uveitis encountered by comprehensive ophthalmologists is anterior uveitis [2]. Intermediate (vitreous), posterior...

Iris-claw IOL implantation: Indications, outcomes and complications

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. A comprehensive study evaluating the clinical indications, visual outcomes and complication rates...

My Top Five: Emerging robotic and automated innovations in ophthalmological surgery

Robotic technology is redefining the landscape of ophthalmological surgery by enabling micron-level precision and control beyond human capability. Intraocular microsurgery remains challenging to perform, with concerns about accuracy, tremor, precision, depth perception and dexterity. Moreover, conventional surgical tools have only...

Cataract surgery in uveitis patients

Cataract formation is a common complication of uveitis, causing up to 40% of vision loss in these patients. Cataract results from inflammation +/- corticosteroid therapy and is usually posterior subcapsular, but a small proportion have a rapid increase in nuclear...