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Macular imagery: observing the visual sensations pre- and post-Jetrea injections

25 September 2021 | | EYE - Vitreo-Retinal, EYE - General
A 63-year-old woman, a professional painter, was diagnosed with vitreomacular traction (VMT) in 2017. She had a history of metamorphopsia, drop in visual acuity (VA) in the left eye (6/6 in the RE; 6/18 in the LE), foveal vitreomacular traction...

Could the sclera be key to glaucoma?

1 December 2017 | | EYE - Glaucoma
The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...

Neonatal hypoxic ischaemic encephalopathy with imaging abnormalities in the occipital lobe – how to counsel the parents

5 April 2022 | | EYE - Neuro-ophthalmology, EYE - Imaging, EYE - General
Case A baby boy, with a background of intrauterine growth restriction, was born at 37 weeks and three days gestation via forceps delivery. The baby was born in poor condition, with low heart rate, poor respiratory rate, poor colour and...

Randomisation, confounding & observational methods in ophthalmic epidemiology

1 June 2022 | | EYE - General
Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...

Roles, titles, and the healthcare scientist

2 August 2024 | | EYE - Imaging
Within the typical eye unit, there are lots of ‘Ophth’ job titles. We as ophthalmic professionals mostly know what these titles mean, but do our patients and junior staff? During my career I have had many and varied job titles,...

The management of chronic uveitis

1 October 2015 | | EYE - Vitreo-Retinal
A 40-year-old company executive is referred from another unit with recurrent anterior and posterior uveitis for 12 months and the inflammatory markers are raised. Review of systems This is a case of chronic uveitis which needs a thorough workup and...

Behind the eyes: Unravelling the mystery of a painless progressive proptosis

4 February 2025 | | EYE - Oculoplastic, EYE - Orbit, EYE - Pathology
Orbital fungal infections have the potential to give rise to serious complications. While these infections typically originate in the sinuses, patients may initially exhibit ocular symptoms. As a result of the diverse and often vague clinical manifestations (especially during the...

Ocular mucous membrane pemphigoid: the importance of early detection and treatment

1 August 2014 | | EYE - Oculoplastic, EYE - Orbit
Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterised by subepithelial bullae. The ocular manifestation of MMP, ocular mucous membrane pemphigoid (OMMP), is a sight-threatening condition characterised by conjunctival cicatricial changes associated with corneal vascularisation and scarring....

The eye surgeon and eye physician together: the joint ophthalmic clinic

3 February 2023 | | EYE - General
Since the early 19th century, physicians and surgeons have been working together in eye clinics and hospitals to bring about the best outcome for the patients. From the early Babylonian age, important advances in ophthalmic knowledge arose in a stuttered...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

1 December 2016 | | EYE - Vitreo-Retinal
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

Strategies for managing neovascular AMD and DMO in routine clinical care

1 October 2015 | | EYE - Vitreo-Retinal
Treatment practice in the management of neovascular age-related macular degeneration (AMD) and diabetic macular oedema (DMO) illustrate increasing adoption of patient-tailored treatment approaches based on initial diagnosis and regular monitoring of imaging and visual outcomes in routine clinical care. The...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...