Journal Reviews
New prognostic model for multiple sclerosis after optic neuritis presentation
The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...
Test combination which could detect prodromal Alzheimer disease
The authors prospectively recruited a convenience sample of individuals aged over 65 and either with a diagnosis of mild cognitive impairment (MCI) due to Alzheimer disease or normal cognition. Other types of dementia and severe neurological conditions were excluded. All...
Anatomical variations of the nasolacrimal system
The authors report a retrospective observational case series of 734 dacryocystography images; 689 from adult patients and 45 from paediatric patients. Of these 734 images, 35 (4.8%) were found to have an anatomical variant where the nasolacrimal duct emerged from...
DIGIROP efficacy for detecting treatment-requiring retinopathy of prematurity (TR-ROP)
This article examines the efficacy of using the DIGIROP online prediction model in estimating the risk of retinopathy of prematurity (ROP) requiring treatment in two Portuguese hospitals. Portuguese screening criteria for ROP mirrors that of the UK (<32 weeks gestation...
Divergence insufficiency esotropia is increasingly more common and new theory of aetiology
The authors present a retrospective case review of acquired esotropia. An internal database was reviewed for cases of esotropia and divergence insufficiency between 1978 and 2018 and seen by a single ophthalmologist. Patients with initial presentation of esotropia onset after...
Retrospective safety assessment of apraclonidine for diagnosis of Horner’s syndrome in children
Apraclonidine has been shown to reverse the anisocoria in Horner’s syndrome, with some reports of partial ptosis resolution. Side-effects of apraclonidine have been reported especially in children under six months old. The authors present a retrospective safety study of using...
ISBCS versus DSBCS
This is a retrospective study of 53 children who had immediate sequential bilateral cataract surgery (ISBCS) (37/53) or delayed sequential bilateral cataract surgery (DSBCS) (16/53) at a tertiary referral paediatric hospital in Toronto, Canada. Clear visual axis was the measure...
Eyelid position assessment using mobile phone photography and simple measurement tool in children
Inspired by the difficulty to obtain the gold-standard measurement of eyelid position in children, the authors present a proof-of-concept study of a simple measurement tool paired with digital photography. Patients and their siblings between the ages of one-year to 21-years-old,...
Associations with ocular surface disease in high school children
The authors aimed to determine the prevalence of ocular surface symptoms in a high school population and to evaluate its association with contact lens wear and other factors. The study had a population of 3240 students. This was a cross-sectional...
Effect of syringe-filling technique and risk for endophthalmitis after intravitreal injection of anti-VEGF agents
In this retrospective study the authors compare the risk for post-injection endophthalmitis between different anti-vascular endothelial growth factor (VEGF) agents and syringe preparation technique. This multicentre study included 197,402 injections. The drugs included in this study were three Anti-VEGF agents...
Morphological and functional outcome after subthreshold laser coagulation with a frequency-doubled Nd:YAG laser
Central serous chorioretinopathy; Retinal imaging; Retinal laser coagulation
Are any precautions needed when performing cataract surgery in thrombocytopenic patients?
In this retrospective multi-centre study, charts for 196 eyes of 150 thrombocytopenic patients were reviewed. The mean preoperative platelet level was 73.0 ± 20.5 × 103/μL (median of 76.0 × 103/μL), with a range of 17 to 100 × 103/μL...
