Ocular adnexal marginal zone b-cell lymphoma
5 August 2020
| Jonathan Chan
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EYE - Pathology, EYE - Oncology
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conjunctiva, epidemiology, eye lids, neoplasia, orbit
This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...
Quality of life concerns after uveal melanoma diagnosis
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
5 August 2020
| Annes Ahmeidat
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EYE - Pathology, EYE - Oncology
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Brachytherapy, Treatment practices, Uveal melanoma
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
Support for patients with nystagmus
This is a qualitative study in patients with nystagmus identified through regional clinics, charity events and the Royal National Institute of Blind People (RNIB). Two hundred and fifty-one participants were identified, with 184 respondents included in the study. Fifty-six percent...
Mediation of vertical vergence
The authors hypothesised that if vertical vergence were mediated by vertical rectus muscles, then the eye that moves during a vertical fusion task would produce larger vertical vergence when abducted versus adducted. Similarly, if mediated by the oblique muscles then...
Lang Stereopad comparisons
The aim of this study was to compare the effectiveness of the Lang Stereopad in detecting and measuring stereopsis in a population with normal visual parameters. The Lang Stereopad was compared directly to the Frisby, TNO and Lang II stereotests...
Silicone oil migration presenting as an eyelid cyst
The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...
Medical treatment of orbital lymphatic malformations
This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...
CD73 in aggressive basal cell carcinoma
This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...
Duane’s retraction syndrome (DRS)
The authors aimed to review all cases of DRS presenting to a tertiary paediatric eye clinic in South Africa during a 20-year period. This was a retrospective study in Cape Town involving 120 patents (80 mixed race, 24 black and...
Surgical results in spinocerebellar ataxia (SCA)
Patients with SCA frequently develop ocular motility abnormalities including nystagmus, abnormal smooth pursuits, dysmetric saccades, divergence paresis and ophthalmoplegia. Incidence of diplopia is higher in SCA type 3. The purpose of this study was to evaluate surgical responses and outcomes...
Risk factors for surgical failure in nasolacrimal duct obstruction
This study considered possible associated patient anatomic or physiologic factors for initial surgical failure of nasolacrimal duct obstruction (NLDO). This was a retrospective study analysing risk factors for patients with successful initial surgery in comparison to patients requiring multiple surgeries....
