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Effects of topical anaesthetic on intraocular pressure

This prospective interventional study assessed the effects of repeated intraocular pressure (IOP) using Goldmann applanation tonometry and applanation resonance tonometry in six volunteers. Previous literature supports IOP reduction using repeated applanation tonometry. Repeated IOP measures were taken alternately on 12...

Liquid adhesive bandage for clear corneal cataract incisions

This paper reports a prospective randomised controlled trial of patients undergoing routine phacoemulsification with a 2.75mm clear corneal incision and followed up for 14 days postoperatively. They evaluated wound edge closure, surgically induced astigmatism and foreign body sensation after use...

Effects of idiopathic intracranial hypertension on the optic nerves

The authors review the latest evidence regarding how the optic nerves are affected by idiopathic intracranial hypertension (IIH), possible pathophysiology and methods of assessment. IIH is described as a clinical syndrome of raised intracranial pressure of unknown aetiology. A systematic...

Evaluation of fluocinolone acetonide in the management of BRC

This is a single-centre, retrospective, intervention study of 15 eyes of birdshot retinochoroiditis (BRC) patients who received Iluvein, with a mean follow-up period of 31 months. Five eyes had previously received dexamethasone intravitreal implant 0.7mg (Ozurdex). Fluorescein angiography (FA) showed...

Lacquer cracks

The purpose of this Japanese study was to analyse the morphologic features and natural progression patterns of lacquer cracks (LC). The presence of linear hyperfluorescence on the fundus fluorescein angiography (FFA) was used as the standard for diagnosing the presence...

Radiation maculopathy

This is a retrospective non-randomised study of 13 consecutive eyes of 13 patients affected by radiation maculopathy secondary to eye irradiation for primary uveal melanoma (Iodine-125 brachytherapy). All patients were treated with a single intravitreal 0.7mg dexamethasone implant and full...

Managing orbital compartment syndrome

This experimental study using cadaveric models was done to evaluate the surgical technique effective in relieving orbital compartment syndrome. Twelve cadaveric orbits were injected with blood analogue stained with fluorescein. Pressure probes were inserted in superotemporal (advanced 40mm into orbit)...

OCT changes in chronic optic neuropathy

The authors evaluated optical coherence tomography (OCT) angiography in 10 patients who suffered various types of chronic optic neuropathies. Glaucoma is known to cause a decrease in peripapillary perfused capillary density on OCT angiography. However, other optic neuropathies have not...

Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?

This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...