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Can closing the eyelid during riboflavin induction phase of crosslinking increase corneal thickness?

Corneal crosslinking (CXL) with riboflavin and UVA irradiation is the standard treatment for preventing progression of keratoconus. Thinning of the cornea during the riboflavin loading phase was reported in previous studies which used riboflavin with dextran. A minimum stromal thickness...

Positives and negatives of managing diplopia in adults with prisms

This study recruited consecutive patients prescribed prisms during a two-year period, within set criteria of a deviation up to 30 prism diopters, good fusion, willingness to wear prisms and no previous unsuccessful use of prisms. The majority of cases had...

Measurement considerations in OCT results with suspected glaucoma

The purpose of this study was to determine retinal nerve fibre (RNFL) thickness parameters and assess the relationship between the cup-to-disc (CD) ratio and RNFL measurements of paediatric patients who had optic nerve appearance suspicious for glaucoma based on enlarged...

Retinal changes prior to hydroxychloroquine toxicity

In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...

Changes in the choroid after atropine for amblyopic and fellow eyes

The purpose of this study was to compare the effects of atropine on the thickness and structure of the choroid between amblyopic and fellow eyes. This study included 16 patients: five males, 11 females. Median age at ocular coherence tomography...

Using OCT to screen and monitor Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...

Comparison of methods of central corneal thickness measurement in glaucoma

This prospective study was done to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and disc-mounted ultrasound pachymeter in glaucoma patients. Sixty-five patients were included in the study. Patients with corneal diseases, corneal astigmatism >3 diopters...

Effects of clonidine vs. placebo

The purpose of this study was to measure postoperative agitation using a standardised scale and evaluate whether it is reduced if given clonidine prior to strabismus surgery as compared to placebo. The scales included the Pediatric Anesthesia Emergence Delirium (PAED)...

GA vs. office measures of axial length

Axial lengths were compared in an office setting versus under general anaesthetic (GA) to determine if awake office measures are feasible and whether differences in measures occur in both settings. The study included 33 eyes of 19 children; 84% male,...

Navigating the retina: the nitty-gritty of slit-lamp fundus examination

The slit-lamp fundus examination can be a difficult and disorientating task for beginners due to the retina being viewed in a non-anatomical orientation, the small area of retina illuminated, and the counterintuitive technique of the examination. This article provides a...

OCT choroidal signs for congenital retinal pigment epithelium hypertrophy

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...

Choroidal and RNFL thickness in patients with OSAS

In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...