The purpose of this study was to compare the effects of atropine on the thickness and structure of the choroid between amblyopic and fellow eyes. This study included 16 patients: five males, 11 females. Median age at ocular coherence tomography assessment was 5.4 years. Amblyopic eyes were more hyperopic than fellow eyes. After atropine, there was a significant increase in hyperopia in both eyes. Median axial length was shorter for both eyes after atropine. Sub foveal choroidal thickness was significantly increased in fellow eyes after atropine along with significant increase in luminal and stromal areas of the choroid. The latter was not significant for amblyopic eyes. Results suggest that function related to the control of choroidal thickness could be inhibited in the amblyopic eye.
Changes in the choroid after atropine for amblyopic and fellow eyes
Reviewed by Fiona Rowe
Changes in choroidal thickness and structure induced by 1% atropine instillation in children with hyperopic anisometropic amblyopia.
CONTRIBUTOR
Fiona Rowe (Prof)
Institute of Population Health, University of Liverpool, UK.
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