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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Hereditary profile of retinal detachment

This review sought to clarify some of the heritable elements of rhegmatogenous retinal detachment (RRD). The familial element of RRD is well established, with the sibling recurrence risk ratio being 2.1 (Mitry and colleagues), and the parent-offspring recurrence risk ratio...

Orbis and FundamentalVR to talk at 100% Optical

The health care technology company teams up with the global non-profit to showcase how simulation, telemedicine and virtual reality (VR) are changing the landscape of cataract surgery education.

Coming to terms with AI

A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...

A brief history of colour vision

Andrew Want takes a look at how colour vision has evolved in humans and animals and how it differs across species. Colour vision is something that we often take for granted, but it has become so intrinsic to the way...

Breakthroughs in the genetics of angle-closure glaucoma

Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference

Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...

SILMO 2019: Anything goes, but sustainability grows

Trying to spot the trends at this year’s SILMO in Paris, one of the largest optical fairs in the world, was a tough ask. Thin metals, especially in rose gold, abounded, but that’s now; tomorrow remained elusive.

Blame the lens – not its position – in refractive surprise

Aetiology of postoperative refractive surprise Weber coined the term “wrong eye, wrong intraocular lens, wrong patient” in 2008 as an aide memoir of major factors believed to underlie refractive surprise – defined as a significant unintended difference between dioptric refraction...

iTrack™ – A different approach to the outflow pathway

Unlike other MIGS which create artificial flow, iTrack™ is a stent-free, tissue-sparing procedure that treats 360° of the conventional outflow pathway to re-establish natural aqueous flow.

Corza Medical climbs Snowdon to support Orbis UK

On Saturday 17th June a team of Corza Medical employees from their Solihull HQ are going to be climbing Mount Snowdon, the highest peak in Snowdonia (Wales).

Congenital dacryocystocele in UK

The authors report the first national study of dacryocystocoeles in UK. They report an incidence of one in 18,597 live births in the UK for congenital dacryocystocele. A prospective observational study of 49 cases of congenital dacryocystocele presenting between September...