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Simplified Ophthalmic Statistics (SOS) Part 1: An introduction to data – how do we classify it and why does it matter?

1 April 2018 | | EYE - General
Introductory statistics courses often start by explaining how data can be classified in different ways. What is not always clear is why you would need to know this. Catey Bunce and Tafadzwa Young-Zvandasara explain. The term data can be applied...

SOS (Simplified Ophthalmic Statistics) Part 4: How to present your statistical analysis

1 October 2019 | | EYE - General
This is the last in this series of short guides which we hope provide some guidance in relation to statistical issues researchers may encounter when conducting research, audit or indeed quality improvement projects. Here we focus on an issue that...

Innovation update: key advances in eyecare transformation in the last year

1 December 2021 | | EYE - Vitreo-Retinal, EYE - Glaucoma, EYE - General
Vishal Shah and his co-authors reflect on examples of innovation in eyecare delivery published in the last year and the implications for the future of eyecare services. The “new normal” is an overused phrase to describe extraordinary measures that have...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

3 February 2023 | | EYE - General
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

Vitreomacular traction: natural course vs. vitrectomy vs. ocriplasmin

3 June 2024 | | EYE - Vitreo-Retinal
Over time, the vitreous gel completely separates from the retina in a process known as a posterior vitreous detachment (PVD). In some instances, however, the vitreous does not detach entirely and remains adherent to the macula. The term vitreomacular traction...

Ocular mucous membrane pemphigoid: the importance of early detection and treatment

1 August 2014 | | EYE - Oculoplastic, EYE - Orbit
Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterised by subepithelial bullae. The ocular manifestation of MMP, ocular mucous membrane pemphigoid (OMMP), is a sight-threatening condition characterised by conjunctival cicatricial changes associated with corneal vascularisation and scarring....

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

1 February 2017 | | EYE - Vitreo-Retinal
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

Is patient masking leading to an increase in post-op infection after eyelid surgery?

21 October 2020 | | EYE - Oculoplastic
Due to the COVID-19 pandemic, the use of facemasks or face coverings in the clinical setting has become necessary. It is important to recognise that facemasks can be a source of infection after eye surgery and consider ways to minimise...

My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Q&A: Mr Goel and Mr Loomba on alcohol delamination and phototherapeutic keratectomy (PTK) for the treatment of recurrent corneal erosion syndrome

14 June 2023 | | EYE - Cornea
Recurrent corneal erosion syndrome is a common, recurrent condition caused by abnormal epithelial adhesion to the underlying basal lamina. Spontaneous breakdown of the corneal epithelium can lead to the sudden onset of ocular pain, blurred vision, tearing and photophobia, typically...

A window to 2024 and beyond?

3 April 2024 | | EYE - Cornea
The connection between the eye and systemic diseases has been acknowledged for millenia. Historical records suggest that ancient civilisations had some understanding of the eye’s significance beyond its primary function in vision. For instance, in ancient Egypt, the ‘Eye of...

My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...