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Importing iron to the retina

In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...

Arterial stiffness and PEX

The authors describe a study of 25 newly diagnosed patients with pseudoexfoliation glaucoma (PEX) and 25 controls to evaluate carotid femoral pulse wave velocity (CF-PWV) values. The CF-PWV was assessed using a noninvasive device by measuring the pulse transmit time...

OCTA and pigment epithelium detachments

Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...

IVT Aflibercept 2mg in nAMD: XTEND at 3 years

This study investigated the long-term, effectiveness and safety of IVT-AFL 2mg for neovascular age-related macular degeneration (nAMD). XTEND was a multicentre, observational, prospective study, which was conducted across 127 centres across 17 countries with a follow-up period of 36 months....

Pseudophakic Monovision: A Clinical Guide

The contents of this small volume should provide useful tips for all ophthalmic practitioners involved with managing patients undergoing cataract surgery. For those ophthalmic clinicians and supporting staff not familiar with the potential options for achieving a spectacle independent refractive...