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2535 results found

Characteristics of cherry red spot on optical coherence tomography

In this study the authors report optical coherence tomography (OCT) characteristics of cherry red spot from three cases of Tay-Sachs and one case of Niemann Pick diseases to determine associated factors and potential visual implications. This was a retrospective case...

Updated staging of LCHADD retinopathy

The authors present their proposal for an updated staging system for Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase (LCHAD) deficiency retinopathy. This is a rare mitochondrial disease due to deficiency of the long chain fatty acid oxidation pathway. Forty patients who were part of...

Longitudinal findings in children with neurofibromatosis type 1

This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...

A novel parameter for angle closure

This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...

Infliximab in treatment of PVR

In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...

Is lens constant optimisation for IOLMaster indispensable in order to achieve a good refractive outcome?

A study of refractive outcomes following cataract surgery was carried out with the aim of comparing the postoperative refractive outcomes against Royal College of Ophthalmologists standards and to determine the extent of association between accuracy of intraocular lens (IOL) power...

The Global Vision Database

The overall goal of the Global Vision Database (GVD) [1] is to develop and deploy new and improved evidence on the prevalence of blindness and vision impairment (VI) globally. It is a repository which allows us to assess the causes...

My top five: Uses of artificial intelligence in ophthalmology

Artificial Intelligence (AI) has emerged as a prominent topic of discussion within the field of ophthalmology, captivating researchers and practitioners alike. Although recent attention has been drawn to the integration of AI in ophthalmology, it’s important to recognise that AI...

My Top Five: Uses of artificial intelligence in ophthalmology

Artificial Intelligence (AI) has emerged as a prominent topic of discussion within the field of ophthalmology, captivating researchers and practitioners alike. Although recent attention has been drawn to the integration of AI in ophthalmology, it’s important to recognise that AI...

Ultrasound biomicroscopy (part 2): primary angle closure

Patients with primary angle closure or primary angle closure glaucoma [PAC(G)] comprise a significant subgroup affecting around 10% of glaucoma patients amongst Caucasians. Assessment of the patient with angle closure, or narrow angles, requires gonioscopy. However, whilst identifying the presence...

Postop esotropia re-drift

The authors aimed to investigate the rate and onset of development of re-drift after infantile esotropia surgery and identify factors associated with this. This was a retrospective study of 112 patients with a mean postoperative follow-up of 9.5 years. Consecutive...