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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

1 October 2016 | | EYE - Vitreo-Retinal
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Hypothyroidsim and acute central serous chorioretinopathy – is there a link?

1 April 2020 | | EYE - Vitreo-Retinal
This cross-sectional study included 71 consecutive acute central serous chorioretinopathy (CSC) patients and 70 age-matched healthy control subjects. Systemic findings, including serum levels of thyroid hormones, thyroid stimulating hormone (TSH), mean arterial pressure (MAP), pulse rate, serum lipid levels and...

Certifying patients as visually impaired: the start of a journey

1 October 2019 | | EYE - General
In March 2017 there were 290,475 people registered as either visually impaired or severely visually impaired in the UK [1]. Patients registered as sight impaired benefit from financial support as well as practical help. Practical help is provided by social...

Is patient masking leading to an increase in post-op infection after eyelid surgery?

21 October 2020 | | EYE - Oculoplastic
Due to the COVID-19 pandemic, the use of facemasks or face coverings in the clinical setting has become necessary. It is important to recognise that facemasks can be a source of infection after eye surgery and consider ways to minimise...

More sensitive visual acuity test for age-related macular degeneration

1 October 2016 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

What's trending Aug/Sep 2020

5 August 2020 | | EYE - General
Life, at least from headlines, is certainly awakening again. #DominicCummings #Specsavers #BarnardCastleeyetest In one of the bizarre developments of #coronaviruslife, Dominic Cummings, Boris Johnson’s most senior advisor, claimed he drove to Barnard Castle from Durham to test his eyesight. He...

Making sense of the orthoptic assessment

1 April 2020 | | EYE - Cataract
Following the Specialty Trainee article on this topic in the February/March 2020 issue, Joe Smith provides a more detailed breakdown of the orthoptic report. Orthoptists investigate, diagnose and manage a wide variety of patients with varying problems. In this article,...

Macular holes: A brief review

1 August 2017 | | EYE - Vitreo-Retinal
The classification of macular holes has been modernised by OCT findings. This is a brief review and encompasses the historical literature on macular holes. A macular hole is an anatomical discontinuation of the neurosensory retina at the centre of the...

The David J Apple International Laboratory for Ocular Pathology – a legacy of pioneering IOL research

1 October 2016 | | EYE - Cataract, EYE - Refractive
David Apple and Gerd Auffarth. The Apple Lab at the David J Apple Center for Vision Research in Heidelberg is a thriving international laboratory for research into intraocular devices. The lab continues the work of David J Apple, a world-renowned...

Development of a modern surgical simulation suite to promote safer ophthalmic surgical training

5 August 2020 | | EYE - Cataract, EYE - Refractive, EYE - Vitreo-Retinal, EYE - Orbit, EYE - General
For trainees, having access to surgical simulation equipment is more important than ever. The authors describe the creation of a bespoke teaching and training suite in Glasgow to help trainees develop their skills and promote surgical excellence. Simulation has become...

Corneal transplantation in the United Kingdom: are we blind to the challenges that still exist after the Organ Donation Bill?

28 November 2022 | | EYE - Cornea, EYE - General
Corneal transplantation (CT) is a significant treatment option for a huge number of patients in the United Kingdom (UK) [1]. For an individual, CT results in a substantial improvement in quality of life. Penetrating keratoplasty with full thickness grafting has...

Diabetic Macular Oedema

1 December 2013 |
Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...