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Post hoc analysis of the CANTREAT randomised trial

CANTREAT, a Canadian multicentre two-year randomised trial compares treat and extend treatment (T&E) relative to the monthly administration of Ranibizumab in nAMD. Two-hundred and eighty-five treatment-naïve patients with nAMD were randomised to receive either a once-monthly dosing or T&E regimen...

Behind the eyes: Unravelling the mystery of a painless progressive proptosis

Orbital fungal infections have the potential to give rise to serious complications. While these infections typically originate in the sinuses, patients may initially exhibit ocular symptoms. As a result of the diverse and often vague clinical manifestations (especially during the...

Intraocular Lens Surgery

This book is a valuable update on understanding IOL surgery for ophthalmologists in training and in practice. Broadly, the book is divided into six sections dealing with three main concepts: 1) IOL selection for routine and complex scenarios; 2) IOL...

Understanding vasoproliferative retinal tumours

Syed Irtiza Ali Shah explores this rare and unusual condition through a fascinating case presentation. Vasoproliferative tumours of the retina (VPTR) are a vascular mass with an associated exudative retinopathy alongside the presence of minimally dilated feeder vessels. This is...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

Orthoptic slit-lamp

Adaptations are described that allow the slit-lamp to be used to document squint disorders. Changes are made in the observation system, illumination system, for recording clinical findings and visualisation of clinical findings. The author includes the use of minus lens...

Cyclo spray vs. drops

The purpose of this study was to investigate whether cyclo spray is better tolerated than cyclo drops and to assess the adequacy of cycloplegia achieved by spray for objective refraction. Cyclo drops were given to 72 children and cyclo spray...

Using video-oculography to record monocular eye movements

The aim of this study was to examine the characteristics of monocular eye movements recorded using video-oculography (VOG). VOG monocular recording has become increasingly popular in comparison to electro-oculographic binocular recording, due to its simple technique. The authors evaluated the...

From paper to digital: Real lessons for a sustainable NHS digital future

Portsmouth's OpenEyes implementation reveals why healthcare digital transformation needs honest evaluation, proper clinical leadership resourcing and realistic expectations about technology efficiency promises. Like many eye departments across the NHS, we at Portsmouth were drowning in paper. Notes went missing, handwriting...

Patient and public participation shapes biomedical research and access priorities in eye health

Patients, clinicians and clinician-scientists play a valuable role in shaping the future of vision research. Limited funding demands targeted research initiatives that ultimately will shape health policy and practice to secure progress in improving patient outcomes in eye health. This...

Unilateral central scotoma following dengue fever

Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...

Artificial intelligence co-creation for educational learning tools and targeted simulators

Artificial intelligence (AI)-powered tools are becoming increasingly common within clinical practice and medical education, and using AI in simulation as a pure learning tool and for assessment has been widely discussed. Targeted, efficient use of such tools has been shown...